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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

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( jV3 / Jmol ) *1
PDB ID2qri  sequence information (FASTA format)   
RELATED PDB ID2qrs, 2qrt
DescriptorH-2 class I histocompatibility antigen K-B alpha chain, Beta-2 microglobulin, ovalbumin-derived peptide
TitleCrystal structure of a single chain trimer composed of the MHC I heavy chain H-2Kb WT, beta-2microglobulin, and ovalbumin-derived peptide.
Functional KeywordsMHC-I, Ova, Single Chain MHC-I, Glycoprotein, Immune response, Membrane, MHC I, Transmembrane, IMMUNE SYSTEM
Biological sourceMus musculus (house mouse)
Cellular location [UNP - Q91XJ8] Secreted
Organ source [UNP - Q91XJ8] Head, Lung, and Placenta and extra embryonic tissue
[UNP - Q91XJ8] Head
[UNP - Q91XJ8] Lung
[UNP - Q91XJ8] Brain
[UNP - Q91XJ8] Placenta and extra embryonic tissue
Total number of polymer chains2
Total molecular weight94133.8 (the details in Structural Details Page)
AuthorsMitaksov, V.E. , Fremont, D.H. (deposition date : 2007-07-28, release date : 2007-11-06)
Primary citationMitaksov, V. , Truscott, S.M. , Lybarger, L. , Connolly, J.M. , Hansen, T.H. , Fremont, D.H.
Structural engineering of pMHC reagents for T cell vaccines and diagnostics.
Chem.Biol., 14:909 - 922, 2007.(PubMed : 17719490)  (DOI: 10.1016/j.chembiol.2007.07.010)
Experimental methodX-RAY DIFFRACTION ( 2.0[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P01901, Q91XJ8 ) , eF-site , PISA