<Asymmetric unit>
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jV3
PDB ID 1ddx sequence information (FASTA format)
RELATED PDB ID 1cvu , 1dcx , 1dd0 , 6cox , 5cox , 1cqe
Descriptor PROSTAGLANDIN H2 SYNTHASE-2
Title CRYSTAL STRUCTURE OF A MIXTURE OF ARACHIDONIC ACID AND PROSTAGLANDIN BOUND TO THE CYCLOOXYGENASE ACTIVE SITE OF COX-2: PROSTAGLANDIN STRUCTURE
Functional Keywords COX-2, CYCLOOXYGENASE, PROSTAGLANDIN, ARACHIDONATE, ENDOPEROXIDE, OXIDOREDUCTASE
Biological source Mus musculus
(house mouse)
Cellular location
[UNP - Q05769 ]
Microsome membrane; Peripheral membrane protein
Organ source
[UNP - Q05769 ]
Liver
Total number of polymer chains 8
Total molecular weight 260103.2 (the details in Structural Details Page )
Authors Kiefer, J.R. , Pawlitz, J.L. , Moreland, K.T. , Stegeman, R.A. , Gierse, J.K. , Stevens, A.M. , Goodwin, D.C. , Rowlinson, S.W. , Marnett, L.J. , Stallings, W.C. , Kurumbail, R.G.
(deposition date : 1999-11-11, release date : 2000-05-16)
Primary citation Kiefer, J.R. , Pawlitz, J.L. , Moreland, K.T. , Stegeman, R.A. , Hood, W.F. , Gierse, J.K. , Stevens, A.M. , Goodwin, D.C. , Rowlinson, S.W. , Marnett, L.J. , Stallings, W.C. , Kurumbail, R.G.Nature ,
405:97 - 101, 2000.(PubMed : 10811226) (DOI: 10.1038/35011103)
Experimental method X-RAY DIFFRACTION ( 3.00[Å] )
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