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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

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( jV3 / Jmol ) *1
PDB ID2vqt  sequence information (FASTA format)   
RELATED PDB ID2vot, 2vl4, 2vqu, 2vo5, 2je8, 2vr4, 2vjx, 2vmf
DescriptorBETA-MANNOSIDASE (E.C.3.2.1.25)
TitleSTRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES
Functional KeywordsLINEAR FREE ENERGY RELATIONSHIP, TRANSITION STATE MIMIC, HYDROLASE, MANNOSIDASE, GLYCOSIDE HYDROLASE
Biological sourceBACTEROIDES THETAIOTAOMICRON
Total number of polymer chains2
Total molecular weight200474.4 (the details in Structural Details Page)
AuthorsTailford, L.E. , Offen, W.A. , Smith, N.L. , Dumon, C. , Moreland, C. , Gratien, J. , Heck, M.P. , Stick, R.V. , Bleriot, Y. , Vasella, A. , Gilbert, H.J. , Davies, G.J. (deposition date : 2008-03-18, release date : 2008-04-08)
Primary citationTailford, L.E. , Offen, W.A. , Smith, N.L. , Dumon, C. , Morland, C. , Gratien, J. , Heck, M.P. , Stick, R.V. , Bleriot, Y. , Vasella, A. , Gilbert, H.J. , Davies, G.J.
Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4:306 - , 2008.(PubMed : 18408714)  (DOI: 10.1038/nchembio.81)
Experimental methodX-RAY DIFFRACTION ( 2.10[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( Q8AAK6 ) , eF-site , KEGG ( EC 3.2.1.25 ) , PISA