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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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PDB ID2vxo  sequence information (FASTA format)   
RELATED PDB ID2vpi
DescriptorGMP SYNTHASE [GLUTAMINE-HYDROLYZING] (E.C.6.3.5.2)
TitleHUMAN GMP SYNTHETASE IN COMPLEX WITH XMP
Functional KeywordsPROTO-ONCOGENE, PHOSPHOPROTEIN, GMP SYNTHETASE, GUANINE MONOPHOSPHATE SYNTHETASE, CHROMOSOMAL REARRANGEMENT, GLUTAMINE AMIDOTRANSFERASE, GMP BIOSYNTHESIS, NUCLEOTIDE-BINDING, PURINE BIOSYNTHESIS, NUCLEOTIDE METABOLISM, GMPS, CASP8, LIGASE, CYTOPLASM, ATP-BINDING
Biological sourceHOMO SAPIENS (HUMAN)
Cellular location [UNP - P49915] Cytoplasm
Organ source [UNP - P49915] Placenta
[UNP - P49915] Epithelium
Total number of polymer chains2
Total molecular weight156448.6 (the details in Structural Details Page)
AuthorsWelin, M. , Lehtio, L. , Andersson, J. , Arrowsmith, C.H. , Berglund, H. , Collins, R. , Dahlgren, L.G. , Edwards, A.M. , Flodin, S. , Flores, A. , Graslund, S. , Hammarstrom, M. , Johansson, A. , Johansson, I. , Karlberg, T. , Kotenyova, T. , Moche, M. , Nilsson, M.E. , Nyman, T. , Olesen, K. , Persson, C. , Sagemark, J. , Schueler, H. , Thorsell, A.G. , Tresaugues, L. , Van Den Berg, S. , Wisniewska, M. , Wikstrom, M. , Nordlund, P. (deposition date : 2008-07-08, release date : 2008-08-12)
Primary citationWelin, M. , Lehtio, L. , Andersson, J. , Arrowsmith, C.H. , Berglund, H. , Collins, R. , Dahlgren, L.G. , Edwards, A.M. , Flodin, S. , Flores, A. , Graslund, S. , Hammarstrom, M. , Johansson, A. , Johansson, I. , Karlberg, T. , Kotenyova, T. , Moche, M. , Nilsson, M.E. , Nyman, T. , Olesen, K. , Persson, C. , Sagemark, J. , Schueler, H. , Thorsell, A.G. , Tresaugues, L. , Van Den Berg, S. , Wisniewska, M. , Wikstrom, M. , Nordlund, P.
The Structure of Human Gmp Synthetase
To be Published, : - , .
Experimental methodX-RAY DIFFRACTION ( 2.50[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P49915 ) , eF-site , KEGG ( EC 6.3.5.2 ) , PISA