English Statistics Help FAQ Contact Us
Download >>

PDBj (Protein Data Bank Japan) maintains a centralized PDB archive of macromolecular structures and provides integrated tools, in collaboration with the RCSB, the BMRB in USA and the PDBe in EU. PDBj is supported by JST-NBDC and Osaka University.

Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

More images...
View in 3D molecule viewer
( jV3 / Jmol ) *1
PDB ID3b9f  sequence information (FASTA format)   
RELATED PDB ID2ol2, 2hi9
DescriptorProthrombin (E.C.3.4.21.5), protein C inhibitor
Title1.6 A structure of the PCI-thrombin-heparin complex
Functional KeywordsMichaelis complex, Acute phase, Blood coagulation, Calcium, Cleavage on pair of basic residues, Disease mutation, Gamma-carboxyglutamic acid, Glycoprotein, Hydrolase, Kringle, Polymorphism, Protease, Secreted, Serine protease, Zymogen, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
Biological sourceHomo sapiens (human)
Cellular location [UNP - P00734] Secreted, extracellular space
Organ source [UNP - P00734] Mammary gland
[UNP - P00734] Plasma
Total number of polymer chains5
Total molecular weight81647.4 (the details in Structural Details Page)
AuthorsLi, W. , Adams, T.E. , Huntington, J.A. (deposition date : 2007-11-05, release date : 2008-04-22)
Primary citationLi, W. , Adams, T.E. , Nangalia, J. , Esmon, C.T. , Huntington, J.A.
Molecular basis of thrombin recognition by protein C inhibitor revealed by the 1.6-A structure of the heparin-bridged complex.
Proc.Natl.Acad.Sci.Usa, 105:4661 - 4666, 2008.(PubMed : 18362344)  (DOI: 10.1073/pnas.0711055105)
Experimental methodX-RAY DIFFRACTION ( 1.60[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P00734 ) , eF-site , KEGG ( EC 3.4.21.5 ) , PISA