English Statistics Help FAQ Contact Us
Download >>

PDBj (Protein Data Bank Japan) maintains a centralized PDB archive of macromolecular structures and provides integrated tools, in collaboration with the RCSB, the BMRB in USA and the PDBe in EU. PDBj is supported by JST-NBDC and Osaka University.

Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

More images...
View in 3D molecule viewer
( jV3 / Jmol ) *1
PDB ID3bxn  sequence information (FASTA format)   
RELATED PDB ID3bvn
DescriptorHLA-B*1402 extracellular domain/beta-2-microglobulin/Cathepsin A signal sequence octapeptide
TitleThe high resolution crystal structure of HLA-B*1402 complexed with a Cathepsin A signal sequence peptide, pCatA
Functional KeywordsMajor Histocompatibility Complex, MHC, Human Leokocyte Antigen, HLA, HLA-B14, HLA-B*1402, HLA-B1402, HLA-B*14, pCatA, Cathepsin A, Ankylosing Spondylitis, Autoimmunity, IMMUNE SYSTEM
Biological sourceHomo sapiens (human)
Cellular location [UNP - P61769] Secreted
[UNP - P10619] Lysosome
Organ source [UNP - P61769] Peripheral blood
[UNP - P61769] Cervix carcinoma
[UNP - P61769] Dendritic cell
[UNP - P61769] Leukemia
[UNP - P61769] Trachea
[UNP - P61769] Retina, and Skin
[UNP - P61769] Plasma
[UNP - P61769] Urine
[UNP - P10619] Brain
[UNP - P10619] Placenta, and Skin
[UNP - P10619] Platelet
[UNP - P10619] Liver
Total number of polymer chains3
Total molecular weight45402.7 (the details in Structural Details Page)
AuthorsKumar, P. , Vahedi-Faridi, A. , Saenger, W. , Uchanska-Ziegler, B. , Ziegler, A. (deposition date : 2008-01-14, release date : 2009-02-03)
Primary citationKumar, P. , Vahedi-Faridi, A. , Saenger, W. , Merino, E. , Lopez de Castro, J.A. , Uchanska-Ziegler, B. , Ziegler, A.
Structural basis for T cell alloreactivity among three HLA-B14 and HLA-B27 antigens
J.Biol.Chem., 284:29784 - 29797, 2009.(PubMed : 19617632)  (DOI: 10.1074/jbc.M109.038497)
Experimental methodX-RAY DIFFRACTION ( 1.864[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( Q56H30, P61769, P10619 ) , eF-site , PISA