English Statistics Help FAQ Contact Us
Download >>

PDBj (Protein Data Bank Japan) maintains a centralized PDB archive of macromolecular structures and provides integrated tools, in collaboration with the RCSB, the BMRB in USA and the PDBe in EU. PDBj is supported by JST-NBDC and Osaka University.

Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

More images...
View in 3D molecule viewer
( jV3 / Jmol ) *1
PDB ID3cxv  sequence information (FASTA format)   
RELATED PDB ID1n40, 2ij7, 3cxx, 3cxy, 3cxz, 3cy0, 3cy1
DescriptorCytochrome P450 121 (E.C.1.14.-.-)
TitleCrystal structure of the Cytochrome P450 CYP121 A233G mutant from Mycobacterium tuberculosis
Functional Keywordscytochrome P450, CYP121, Mycobacterium tuberculosis, Cytoplasm, Heme, Iron, Metal-binding, Monooxygenase, Oxidoreductase
OXIDOREDUCTASE
Biological sourceMycobacterium tuberculosis
Cellular location [UNP - P0A514] Cytoplasm (By similarity)
Total number of polymer chains1
Total molecular weight44197.1 (the details in Structural Details Page)
AuthorsLeys, D. (deposition date : 2008-04-25, release date : 2008-09-23)
Primary citationMcLean, K.J. , Carroll, P. , Lewis, D.G. , Dunford, A.J. , Seward, H.E. , Neeli, R. , Cheesman, M.R. , Marsollier, L. , Douglas, P. , Smith, W.E. , Rosenkrands, I. , Cole, S.T. , Leys, D. , Parish, T. , Munro, A.W.
Characterization of active site structure in CYP121. A cytochrome P450 essential for viability of Mycobacterium tuberculosis H37Rv.
J.Biol.Chem., 283:33406 - 33416, 2008.(PubMed : 18818197)  (DOI: 10.1074/jbc.M802115200)
Experimental methodX-RAY DIFFRACTION ( 1.70[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P0A514 ) , eF-site , KEGG (EC 1.14.-.- ) , PISA