PDB ID 3db8 sequence information (FASTA format)
RELATED PDB ID 3d5w , 3db6 , 3dbc , 3dbd , 3dbe , 3dbf
Descriptor Polo-like kinase 1 (E.C.2.7.11.21 )
Title Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with Compound 041
Functional Keywords Polo-like kinase 1, Plk1, catalytic domain, small-molecule inhibitor, Kinase, TRANSFERASE
Biological source Danio rerio
(zebra fish)
Organ source
[UNP - Q4KMI8 ]
Embryo
Total number of polymer chains 1
Total molecular weight 36401.2 (the details in Structural Details Page )
Authors Elling, R.A. , Hanan, E.J. , Lew, W. , Romanowski, M.J.
(deposition date : 2008-05-30, release date : 2008-10-07)
Primary citation Hanan, E.J. , Fucini, R.V. , Romanowski, M.J. , Elling, R.A. , Lew, W. , Purkey, H.E. , VanderPorten, E.C. , Yang, W.Bioorg.Med.Chem.Lett. ,
18:5186 - 5189, 2008.(PubMed : 18790636) (DOI: 10.1016/j.bmcl.2008.08.091)
Experimental method X-RAY DIFFRACTION ( 3.15[Å] )
Other Database Information
