PDB ID 1dva sequence information (FASTA format)
RELATED PDB ID 1dan , 1cvw , 1qfk , 1fak
Descriptor CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE PEPTIDE EXOSITE INHIBITOR E-76 AND COAGULATION FACTOR VIIA (E.C.3.4.21.21)
Title Crystal Structure of the Complex Between the Peptide Exosite Inhibitor E-76 and Coagulation Factor VIIA
Functional Keywords protein-peptide complex, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
Biological source Homo sapiens
(human)
Cellular location
[UNP - P08709 ]
Secreted
Organ source LIVER
Total number of polymer chains 9
Total molecular weight 84862.7 (the details in Structural Details Page )
Authors Eigenbrot, C. , Ultsch, M.H.
(deposition date : 2000-01-20, release date : 2000-05-12)
Primary citation Dennis, M.S. , Eigenbrot, C. , Skelton, N.J. , Ultsch, M.H. , Santell, L. , Dwyer, M.A. , O'Connell, M.P. , Lazarus, R.A. Peptide exosite inhibitors of factor VIIa as anticoagulants.
Nature ,
404:465 - 470, 2000.(PubMed : 10761907) (DOI: 10.1038/35006574)
Experimental method X-RAY DIFFRACTION ( 3.00[Å] )
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