PDB ID 1dvx sequence information (FASTA format)
RELATED PDB ID 1bmz , 1dvq , 1dvs , 1dvt , 1dvu , 1dvy , 1dvz
Descriptor TRANSTHYRETIN / DICLOFENAC COMPLEX
Title CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN IN COMPLEX WITH DICLOFENAC
Functional Keywords THYROXINE TRANSPORT, SIGNALING PROTEIN, HORMONE/GROWTH FACTOR COMPLEX
Biological source Homo sapiens
(human)
Cellular location
[UNP - P02766 ]
Secreted
Organ source
[UNP - P02766 ]
Liver
[UNP - P02766 ]
Platelet
[UNP - P02766 ]
Brain, Cajal-Retzius cell, and Fetal brain cortex
[UNP - P02766 ]
Plasma
[UNP - P02766 ]
Cerebrospinal fluid
Total number of polymer chains 2
Total molecular weight 27138.4 (the details in Structural Details Page )
Authors Klabunde, T. , Petrassi, H.M. , Oza, V.B. , Kelly, J.W. , Sacchettini, J.C.
(deposition date : 2000-01-23, release date : 2001-01-23)
Primary citation Klabunde, T. , Petrassi, H.M. , Oza, V.B. , Raman, P. , Kelly, J.W. , Sacchettini, J.C. Rational design of potent human transthyretin amyloid disease inhibitors.
Nature Struct. Biol. ,
7:312 - 321, 2000.(PubMed : 10742177) (DOI: 10.1038/74082)
Experimental method X-RAY DIFFRACTION ( 2.[Å] )
Other Database Information