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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

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<Biological unit>
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PDB ID1dvx  sequence information (FASTA format)   
RELATED PDB ID1bmz, 1dvq, 1dvs, 1dvt, 1dvu, 1dvy, 1dvz
DescriptorTRANSTHYRETIN / DICLOFENAC COMPLEX
TitleCRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN IN COMPLEX WITH DICLOFENAC
Functional KeywordsTHYROXINE TRANSPORT, SIGNALING PROTEIN, HORMONE/GROWTH FACTOR COMPLEX
Biological sourceHomo sapiens (human)
Cellular location [UNP - P02766] Secreted
Organ source [UNP - P02766] Liver
[UNP - P02766] Platelet
[UNP - P02766] Brain, Cajal-Retzius cell, and Fetal brain cortex
[UNP - P02766] Plasma
[UNP - P02766] Cerebrospinal fluid
Total number of polymer chains2
Total molecular weight27138.4 (the details in Structural Details Page)
AuthorsKlabunde, T. , Petrassi, H.M. , Oza, V.B. , Kelly, J.W. , Sacchettini, J.C. (deposition date : 2000-01-23, release date : 2001-01-23)
Primary citationKlabunde, T. , Petrassi, H.M. , Oza, V.B. , Raman, P. , Kelly, J.W. , Sacchettini, J.C.
Rational design of potent human transthyretin amyloid disease inhibitors.
Nature Struct. Biol., 7:312 - 321, 2000.(PubMed : 10742177)  (DOI: 10.1038/74082)
Experimental methodX-RAY DIFFRACTION ( 2.[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P02766 ) , eF-site , PISA