PDB ID 3ene sequence information (FASTA format)
Descriptor Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (E.C.2.7.1.153)
Title Complex of PI3K gamma with an inhibitor
Functional Keywords lipid kinase, phosphoinositide, inhibitor, 3-kinase, signaling, pyrazolopyrimidine, PIK-208, S2, Kinase, Transferase
Biological source Homo sapiens
(Human)
Organ source
[UNP - P48736 ]
Pancreas
Total number of polymer chains 1
Total molecular weight 110072.2 (the details in Structural Details Page )
Authors Apsel, B. , Blair, J.A. , Gonzalez, B.Z. , Nazif, T.M. , Feldman, M.E. , Williams, R.L. , Shokat, K.M. , Knight, Z.A.
(deposition date : 2008-09-25, release date : 2008-10-14)
Primary citation Apsel, B. , Blair, J.A. , Gonzalez, B. , Nazif, T.M. , Feldman, M.E. , Aizenstein, B. , Hoffman, R. , Williams, R.L. , Shokat, K.M. , Knight, Z.A.Nat.Chem.Biol. ,
4:691 - 699, 2008.(PubMed : 18849971) (DOI: 10.1038/nchembio.117)
Experimental method X-RAY DIFFRACTION ( 2.400[Å] )
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