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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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PDB ID1dx4  sequence information (FASTA format)   
DescriptorACETYLCHOLINESTERASE (E.C.3.1.1.7)
TitleACHE FROM DROSOPHILA MELANOGASTER COMPLEX WITH TACRINE DERIVATIVE 9-(3-PHENYLMETHYLAMINO)-1,2,3,4-TETRAHYDROACRIDINE
Functional KeywordsHYDROLASE (SERINE ESTERASE), HYDROLASE, SERINE ESTERASE, SYNAPSE, MEMBRANE, NERVE, MUSCLE, SIGNAL, NEUROTRANSMITTER DEGRADATION, GLYCOPROTEIN, GPI-ANCHOR, ALTERNATIVE SPLICING
Biological sourceDROSOPHILA MELANOGASTER (FRUIT FLY)
Cellular location [UNP - P07140] Cell junction, synapse
Organ source [UNP - P07140] Embryo, and Pupae
Total number of polymer chains2
Total molecular weight66311.6 (the details in Structural Details Page)
AuthorsHarel, M. , Silman, I. , Sussman, J.L. (deposition date : 1999-12-20, release date : 2000-07-21)
Primary citationHarel, M. , Kryger, G. , Rosenberry, T.L. , Mallender, W.D. , Lewis, T. , Fletcher, R.J. , Guss, J.M. , Silman, I. , Sussman, J.L.
Three-Dimensional Structures of Drosophila Melanogaster Acetylcholinesterase and of its Complexes with Two Potent Inhibitors
Protein Sci., 9:1063 - , 2000.(PubMed : 10892800)
Experimental methodX-RAY DIFFRACTION ( 2.7[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P07140 ) , eF-site , KEGG ( EC 3.1.1.7 ) , PISA