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MineSummary [2zb3]

Summary Structural Experimental Function Sequence Neighbor Download Link

<Asymmetric unit>

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( jV3 / Jmol ) *1
PDB ID2zb3  sequence information (FASTA format)   
RELATED PDB ID2zb4, 2zb7, 2zb8
DescriptorProstaglandin reductase 2 (E.C.1.3.1.48)
TitleCrystal structure of mouse 15-ketoprostaglandin delta-13-reductase in complex with NADPH
Functional KeywordsRossmann fold, OXIDOREDUCTASE
Biological sourceMus musculus (Mouse)
Cellular location [UNP - Q8VDQ1] Cytoplasm (By similarity)
Organ source [UNP - Q8VDQ1] Cerebellum, Embryonic heart, Mammary gland, and Medulla oblongata
[UNP - Q8VDQ1] Mammary tumor
Total number of polymer chains1
Total molecular weight38944 (the details in Structural Details Page)
AuthorsWu, Y.H. , Wang, A.H.J. , Ko, T.P. , Guo, R.T. , Hu, S.M. , Chuang, L.M. (deposition date : 2007-10-16, release date : 2008-09-30)
Primary citationWu, Y.H. , Ko, T.P. , Guo, R.T. , Hu, S.M. , Chuang, L.M. , Wang, A.H.J.
Structural basis for catalytic and inhibitory mechanisms of human prostaglandin reductase PTGR2.
Structure, 16:1714 - 1723, 2008.(PubMed : 19000823)  (DOI: 10.1016/j.str.2008.09.007)
Experimental methodX-RAY DIFFRACTION ( 2.0[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( Q8VDQ1 ) , eF-site , KEGG ( EC 1.3.1.48 ) , PISA