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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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( jV3 / Jmol ) *1
PDB ID1m1x  sequence information (FASTA format)   
RELATED PDB ID1jv2, 1m1u
DescriptorIntegrin alpha-V, Integrin beta-3
TitleCRYSTAL STRUCTURE OF THE EXTRACELLULAR SEGMENT OF INTEGRIN ALPHA VBETA3 BOUND TO MN2+
Functional KeywordsGENU, HYBRID DOMAIN, BETA-TAIL DOMAIN, PSI DOMAIN, EGF DOMAIN, MIDAS, ADMIDAS, CAGE MOTIF, PROPELLER, A-DOMAIN, THIGH DOMAIN, CALF DOMAIN, CELL ADHESION
Biological sourceHomo sapiens (human)
Cellular location [UNP - P05106] Membrane; Single-pass type I membrane protein
Organ source [UNP - P05106] Osteoclastoma
[UNP - P05106] Blood
[UNP - P05106] Erythroleukemia
[UNP - P05106] Platelet
[UNP - P05106] Placenta
[UNP - P05106] Keratinocyte, and Skeletal muscle
[UNP - P05106] Plasma
Total number of polymer chains9
Total molecular weight186716.8 (the details in Structural Details Page)
AuthorsXiong, J.-P. , Stehle, T. , Zhang, R. , Joachimiak, A. , Frech, M. , Goodman, S.L. , Arnaout, M.A. (deposition date : 2002-06-20, release date : 2002-08-14)
Primary citationXiong, J.P. , Stehle, T. , Zhang, R. , Joachimiak, A. , Frech, M. , Goodman, S.L. , Arnaout, M.A.
Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand.
Science, 296:151 - 155, 2002.(PubMed : 11884718)  (DOI: 10.1126/science.1069040)
Experimental methodX-RAY DIFFRACTION ( 3.3[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P05106 ) , GenBank/DDBJ/EMBL (GB - 14743192) , eF-site , PISA