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MineSummary [1m73]

Summary Structural Experimental Function Sequence Neighbor Download Link

<Asymmetric unit>

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PDB ID1m73  sequence information (FASTA format)   
RELATED PDB ID1ula
DescriptorPurine nucleoside phosphorylase (E.C.2.4.2.1)
TitleCRYSTAL STRUCTURE OF HUMAN PNP AT 2.3A RESOLUTION
Functional KeywordsPurine Nucleoside Phosphorylase, drug design, crystallography, synchrotron, TRANSFERASE
Biological sourceHomo sapiens (human)
Organ source [UNP - P00491] Tongue
[UNP - P00491] Ovary
[UNP - P00491] Platelet
Total number of polymer chains1
Total molecular weight32342.2 (the details in Structural Details Page)
AuthorsDe Azevedo Jr., W.F. , Marangoni Dos Santos, D. , Canduri, F. , Santos, G.C. , Olivieri, J.R. , Silva, R.G. , Basso, L.A. , Palma, M.S. , Santos, D.S. (deposition date : 2002-07-18, release date : 2003-09-16)
Primary citationde Azevedo, W.F.Jr. , Canduri, F. , dos Santos, D.M. , Silva, R.G. , de Oliveira, J.S. , de Carvalho, L.P.S. , Basso, L.A. , Mendes, M.A. , Palma, M.S. , Santos, D.S.
Crystal structure of human purine nucleoside phosphorylase at 2.3Å resolution.
Biochem.Biophys.Res.Commun., 308:545 - 552, 2003.(PubMed : 12914785)  (DOI: 10.1016/S0006-291X(03)01431-1)
Experimental methodX-RAY DIFFRACTION ( 2.3[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P00491 ) , eF-site , KEGG ( EC 2.4.2.1 ) , PISA