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MineSummary [3ecs]

Summary Structural Experimental Function Sequence Neighbor Download Link

<Asymmetric unit>
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PDB ID3ecs  sequence information (FASTA format)   
DescriptorTranslation initiation factor eIF-2B subunit alpha
TitleCrystal structure of human eIF2B alpha
Functional Keywordseukaryotic translation initiation factor 2Balpha (eIF2Balpha), guanine nucleotide exchange factor (GEF), translation, initiation, stress response, Disease mutation, Initiation factor, Protein biosynthesis, Structural Genomics, RIKEN Structural Genomics/Proteomics Initiative, RSGI
TRANSLATION
Biological sourceHomo sapiens (human)
Total number of polymer chains8
Total molecular weight283028.5 (the details in Structural Details Page)
AuthorsHiyama, T.B. , Ito, T. , Yokoyama, S. , RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date : 2008-09-01, release date : 2009-09-01)
Primary citationHiyama, T.B. , Ito, T. , Imataka, H. , Yokoyama, S.
Crystal Structure of the alpha Subunit of Human Translation Initiation Factor 2B
J.Mol.Biol., : - , 2009.(PubMed : 19631657)  (DOI: 10.1016/j.jmb.2009.07.054)
Experimental methodX-RAY DIFFRACTION ( 2.65[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( Q14232 ) , eF-site , PISA