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MineSummary [3eft]

Summary Structural Experimental Function Sequence Neighbor Download Link

<Asymmetric unit>
= <Biological unit>

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PDB ID3eft  sequence information (FASTA format)   
DescriptorCarbonic anhydrase 2 (E.C.4.2.1.1)
TitleCrystal structure of the complex between Carbonic Anhydrase II and a spin-labeled sulfonamide incorporating TEMPO moiety
Functional Keywordscarbonic anhydrase, inhibitors, crystal structure, Radicals, OXO-ACID, LYASE
Biological source [UNP - P00918] Homo sapiens (Human)
Cellular location [UNP - P00918] Cytoplasm
Organ source [UNP - P00918] Urinary bladder
[UNP - P00918] Ovary
Total number of polymer chains1
Total molecular weight29976.3 (the details in Structural Details Page)
AuthorsTemperini, C. , Cecchi, A. , Scozzafava, A. , Supuran, C.T. (deposition date : 2008-09-10, release date : 2009-09-08)
Primary citationCiani, L. , Cecchi, A. , Temperini, C. , Supuran, C.T. , Ristori, S.
Dissecting the Inhibition Mechanism of Cytosolic versus Transmembrane Carbonic Anhydrases by ESR
J.Phys.Chem.B, 113:13998 - 14005, 2009.(PubMed : 19778001)  (DOI: 10.1021/jp906593c)
Experimental methodX-RAY DIFFRACTION ( 1.85[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P00918 ) , eF-site , KEGG ( EC 4.2.1.1 ) , PISA