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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

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<Biological unit>
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PDB ID1e4e  sequence information (FASTA format)   
RELATED PDB ID1iow, 1iov
DescriptorVANCOMYCIN/TEICOPLANIN A-TYPE RESISTANCE PROTEIN VANA
TitleD-ALANYL-D-LACATE LIGASE
Functional KeywordsLIGASE, CELL WALL, ANTIBIOTIC RESISTANCE, MEMBRANE, PLASMID, PEPTIDOGLYCAN SYNTHESIS
Biological sourceENTEROCOCCUS FAECIUM
Cellular locationCYTOPLASM
Total number of polymer chains2
Total molecular weight78273.4 (the details in Structural Details Page)
AuthorsRoper, D.I. (deposition date : 2000-07-03, release date : 2001-06-28)
Primary citationRoper, D.I. , Huyton, T. , Vagin, A. , Dodson, G.
The Molecular Basis of Vancomycin Resistance in Clinically Releveant Enterococci: Crsytal Structure of D-Alanyl-D-Lactate Ligase (Vana)
Proc. Natl. Acad. Sci. U.S.A., 97:8921 - , 2000.(PubMed : 10908650)  (DOI: 10.1073/PNAS.150116497)
Experimental methodX-RAY DIFFRACTION ( 2.5[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P25051 ) , eF-site , PISA