PDB ID 2a0z sequence information (FASTA format)
Descriptor Toll-like receptor 3
Title The molecular structure of toll-like receptor 3 ligand binding domain
Functional Keywords leucine rich repeat, solenoid, glycosylation, IMMUNE SYSTEM
Biological source Homo sapiens
(human)
Cellular location
[UNP - O15455 ]
Endoplasmic reticulum membrane; Single-pass type I membrane protein
Organ source
[UNP - O15455 ]
Lung
Total number of polymer chains 11
Total molecular weight 86448.5 (the details in Structural Details Page )
Authors Bell, J.K. , Botos, I. , Hall, P.R. , Askins, J. , Shiloach, J. , Segal, D.M. , Davies, D.R.
(deposition date : 2005-06-17, release date : 2005-08-02)
Primary citation Bell, J.K. , Botos, I. , Hall, P.R. , Askins, J. , Shiloach, J. , Segal, D.M. , Davies, D.R. The molecular structure of the Toll-like receptor 3 ligand-binding domain
Proc.Natl.Acad.Sci.USA ,
102:10976 - 10980, 2005.(PubMed : 16043704) (DOI: 10.1073/pnas.0505077102)
Experimental method X-RAY DIFFRACTION ( 2.400[Å] )
Other Database Information