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<Asymmetric unit>
= <Biological unit>

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PDB ID1e7u  sequence information (FASTA format)   
DescriptorPHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT (E.C.2.7.1.137)
TitleSTRUCTURE DETERMINANTS OF PHOSPHOINOSITIDE 3-KINASE INHIBITION BY WORTMANNIN, LY294002, QUERCETIN, MYRICETIN AND STAUROSPORINE
Functional KeywordsPHOSPHOINOSITIDE 3-KINASE GAMMA, SECONDARY MESSENGER GENERATION, PI3K, PI 3K, WORTMANNIN
Biological sourceSUS SCROFA (WILD BOAR)
Total number of polymer chains1
Total molecular weight110381.8 (the details in Structural Details Page)
AuthorsWalker, E.H. , Perisic, O. , Ried, C. , Stephens, L. , Williams, R.L. (deposition date : 2000-09-08, release date : 2000-11-17)
Primary citationWalker, E.H. , Pacold, M.E. , Perisic, O. , Stephens, L. , Hawkins, P.T. , Whymann, M.P. , Williams, R.L.
Structural Determinations of Phosphoinositide 3-Kinase Inhibition by Wortmannin, Ly294002, Quercetin, Myricetin and Staurosporine
Mol.Cell, 6:909 - , 2000.(PubMed : 11090628)  (DOI: 10.1016/S1097-2765(05)00089-4)
Experimental methodX-RAY DIFFRACTION ( 2.0[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( O02697 ) , eF-site , KEGG ( EC 2.7.1.137 ) , PISA