PDB ID 1e7u sequence information (FASTA format)
Descriptor PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT (E.C.2.7.1.137)
Title STRUCTURE DETERMINANTS OF PHOSPHOINOSITIDE 3-KINASE INHIBITION BY WORTMANNIN, LY294002, QUERCETIN, MYRICETIN AND STAUROSPORINE
Functional Keywords PHOSPHOINOSITIDE 3-KINASE GAMMA, SECONDARY MESSENGER GENERATION, PI3K, PI 3K, WORTMANNIN
Biological source SUS SCROFA
(WILD BOAR)
Total number of polymer chains 1
Total molecular weight 110381.8 (the details in Structural Details Page )
Authors Walker, E.H. , Perisic, O. , Ried, C. , Stephens, L. , Williams, R.L.
(deposition date : 2000-09-08, release date : 2000-11-17)
Primary citation Walker, E.H. , Pacold, M.E. , Perisic, O. , Stephens, L. , Hawkins, P.T. , Whymann, M.P. , Williams, R.L. Structural Determinations of Phosphoinositide 3-Kinase Inhibition by Wortmannin, Ly294002, Quercetin, Myricetin and Staurosporine
Mol.Cell ,
6:909 - , 2000.(PubMed : 11090628) (DOI: 10.1016/S1097-2765(05)00089-4)
Experimental method X-RAY DIFFRACTION ( 2.0[Å] )
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