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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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PDB ID3idm  sequence information (FASTA format)   
RELATED PDB ID3d0l, 2p8m, 3idi, 3idj, 3idg, 3idn
Descriptor2F5 Fab light chain, 2F5 Fab heavy chain, gp41 MPER peptide analog
TitleCrystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 Fab' fragment in complex with gp41 Peptide analog ELD(Nrg)WAS
Functional KeywordsHIV-1, gp41, MPER, 2F5, IMMUNE SYSTEM
Biological sourceHomo sapiens
Total number of polymer chains3
Total molecular weight49530.8 (the details in Structural Details Page)
AuthorsJulien, J.-P. , Bryson, S. , Pai, E.F. (deposition date : 2009-07-21, release date : 2010-02-02)
Primary citationBryson, S. , Julien, J.P. , Hynes, R.C. , Pai, E.F.
Crystallographic definition of the epitope promiscuity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5: vaccine design implications.
J.Virol., 83:11862 - 11875, 2009.(PubMed : 19740978)  (DOI: 10.1128/JVI.01604-09)
Experimental methodX-RAY DIFFRACTION ( 2.24[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , eF-site , PISA