PDB ID 3idm sequence information (FASTA format)
RELATED PDB ID 3d0l , 2p8m , 3idi , 3idj , 3idg , 3idn
Descriptor 2F5 Fab light chain, 2F5 Fab heavy chain, gp41 MPER peptide analog
Title Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 Fab' fragment in complex with gp41 Peptide analog ELD(Nrg)WAS
Functional Keywords HIV-1, gp41, MPER, 2F5, IMMUNE SYSTEM
Biological source Homo sapiens
Total number of polymer chains 3
Total molecular weight 49530.8 (the details in Structural Details Page )
Authors Julien, J.-P. , Bryson, S. , Pai, E.F.
(deposition date : 2009-07-21, release date : 2010-02-02)
Primary citation Bryson, S. , Julien, J.P. , Hynes, R.C. , Pai, E.F. Crystallographic definition of the epitope promiscuity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5: vaccine design implications.
J.Virol. ,
83:11862 - 11875, 2009.(PubMed : 19740978) (DOI: 10.1128/JVI.01604-09)
Experimental method X-RAY DIFFRACTION ( 2.24[Å] )
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