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MineSummary [1eaw]

Summary Structural Experimental Function Sequence Neighbor Download Link

<Asymmetric unit>

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PDB ID1eaw  sequence information (FASTA format)   
RELATED PDB ID1eax
DescriptorSUPPRESSOR OF TUMORIGENICITY 14 (E.C.3.4.21.-), PANCREATIC TRYPSIN INHIBITOR
TitleCRYSTAL STRUCTURE OF THE MTSP1 (MATRIPTASE)-BPTI (APROTININ) COMPLEX
Functional KeywordsHYDROLASE/INHIBITOR, COMPLEX (SERINE PROTEASE INHIBITOR), SERINE PROTEINASE, MATRIX DEGRADATION, INHIBITOR, GLYCOPROTE HYDROLASE
Biological sourceHOMO SAPIENS (HUMAN) ,BOS TAURUS (BOVINE) (the details in Structural Details Page)
Cellular location [UNP - Q9Y5Y6] Membrane; Single-pass type II membrane protein (Probable)
[UNP - P00974] Secreted
Organ source [UNP - Q9Y5Y6] Prostate
[UNP - Q9Y5Y6] Blood, and Muscle
[UNP - Q9Y5Y6] Milk
[UNP - P00974] Adrenal chromaffin
Total number of polymer chains4
Total molecular weight65983 (the details in Structural Details Page)
AuthorsFriedrich, R. , Bode, W. (deposition date : 2001-07-17, release date : 2002-01-28)
Primary citationFriedrich, R. , Fuentes-Prior, P. , Ong, E. , Coombs, G. , Hunter, M. , Oehler, R. , Pierson, D. , Gonzalez, R. , Huber, R. , Bode, W. , Madison, E.L.
Catalytic Domain Structures of Mt-Sp1/Matriptase, a Matrix-Degrading Transmembrane Serine Proteinase
J.Biol.Chem., 277:2160 - 2168, 2001.(PubMed : 11696548)  (DOI: 10.1074/JBC.M109830200)
Experimental methodX-RAY DIFFRACTION ( 2.93[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( Q9Y5Y6, P00974 ) , eF-site , KEGG (EC 3.4.21.- ) , PISA