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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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( jV3 / Jmol ) *1
PDB ID3mbm  sequence information (FASTA format)   
RELATED PDB ID3ike, 3ikf, 3ieq, 3f0g, 3f0e, 3jvh, 3k14, 3ke1
Descriptor2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (E.C.4.6.1.12)
TitleCrystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with cytosine and FoL fragment 717, imidazo[2,1-b][1,3]thiazol-6-ylmethanol
Functional KeywordsNIAID, Seattle Structural Genomics Center for Infectious Disease, SSGCID, IspF, cytosine, MEP pathway, fragment-based drug design, FBDD, Fragments of Life, Isoprene biosynthesis, Lyase, Metal-binding
LYASE
Biological sourceBurkholderia pseudomallei (Pseudomonas pseudomallei)
Total number of polymer chains3
Total molecular weight59576.1 (the details in Structural Details Page)
AuthorsSeattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date : 2010-03-25, release date : 2010-04-07)
Primary citationBegley, D.W. , Edwards, T.E. , Staker, B.L. , Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with cytosine and FoL fragment 717, imidazo[2,1-b][1,3]thiazol-6-ylmethanol
TO BE PUBLISHED, : - , .
Experimental methodX-RAY DIFFRACTION ( 1.800[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( Q63T71 ) , eF-site , KEGG ( EC 4.6.1.12 ) , PISA