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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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PDB ID1eko  sequence information (FASTA format)   
RELATED PDB ID1el3
DescriptorPIG ALDOSE REDUCTASE COMPLEXED WITH IDD384 INHIBITOR (E.C.1.1.1.21)
TitlePIG ALDOSE REDUCTASE COMPLEXED WITH IDD384 INHIBITOR
Functional KeywordsALDOSE REDUCTASE, INHIBITION, DIABETES, OXIDOREDUCTASE
Biological sourceSus scrofa (pig)
Cellular location [UNP - P80276] Cytoplasm
Organ sourceEYE
Total number of polymer chains1
Total molecular weight36958.3 (the details in Structural Details Page)
AuthorsPodjarny, A. (deposition date : 2000-03-09, release date : 2000-05-10)
Primary citationCalderone, V. , Chevrier, B. , Van Zandt, M. , Lamour, V. , Howard, E. , Poterszman, A. , Barth, P. , Mitschler, A. , Lu, J. , Dvornik, D.M. , Klebe, G. , Kraemer, O. , Moorman, A.R. , Moras, D. , Podjarny, A.
The structure of human aldose reductase bound to the inhibitor IDD384.
Acta Crystallogr., D56:536 - 540, 2000.(PubMed : 10771421)  (DOI: 10.1107/S0907444900002341)
Experimental methodX-RAY DIFFRACTION ( 2.2[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P80276 ) , eF-site , KEGG ( EC 1.1.1.21 ) , PISA