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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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PDB ID3m3q  sequence information (FASTA format)   
RELATED PDB ID3afk, 3m3c, 3m3e, 3m3o
DescriptorAnti-tumor lectin (E.C.3.1.21.-)
TitleCrystal Structure of Agrocybe aegerita lectin AAL complexed with Ganglosides GM1 pentasaccharide
Functional Keywordsgalectin, AAL, Ganglosides GM1, Apoptosis, Hydrolase, Lectin, Nuclease
HYDROLASE
Biological sourceAgrocybe aegerita (Black poplar mushroom)
Organ source [UNP - Q6WY08] Fruiting body
Total number of polymer chains4
Total molecular weight36216 (the details in Structural Details Page)
AuthorsFeng, L. , Li, D. , Wang, D. (deposition date : 2010-03-09, release date : 2010-12-01)
Primary citationFeng, L. , Sun, H. , Zhang, Y. , Li, D.F. , Wang, D.C.
Structural insights into the recognition mechanism between an antitumor galectin AAL and the Thomsen-Friedenreich antigen
Faseb J., 24:3861 - 3868, 2010.(PubMed : 20530247)  (DOI: 10.1096/fj.10-159111)
Experimental methodX-RAY DIFFRACTION ( 2.200[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( Q6WY08 ) , eF-site , KEGG (EC 3.1.21.- ) , PISA