PDB ID 3mic sequence information (FASTA format)
RELATED PDB ID 1phm , 3mib , 3mid , 3mie , 3mif , 3mig , 3mih , 3mlj , 3mlk , 3mll
Descriptor Peptidyl-glycine alpha-amidating monooxygenase (E.C.1.14.17.3)
Title Oxidized (Cu2+) peptidylglycine alpha-hydroxylating monooxygenase (PHM) with bound azide obtained by co-crystallization
Functional Keywords OXIDOREDUCTASE, MONOOXYGENASE, BIOACTIVE PEPTIDE ACTIVATION, ASCORBATE
Biological source Rattus norvegicus
(rat)
Cellular location
[UNP - P14925 ]
Cytoplasmic vesicle, secretory vesicle membrane; Single-pass membrane protein
Organ source
[UNP - P14925 ]
Heart atrium
[UNP - P14925 ]
Pituitary
[UNP - P14925 ]
Liver
Total number of polymer chains 1
Total molecular weight 35600.4 (the details in Structural Details Page )
Authors Chufan, E.E. , Eipper, B.A. , Mains, R.E. , Amzel, L.M.
(deposition date : 2010-04-10, release date : 2010-11-24)
Primary citation Chufan, E.E. , Prigge, S.T. , Siebert, X. , Eipper, B.A. , Mains, R.E. , Amzel, L.M. Differential Reactivity Between the Two Copper Sites of Peptidylglycine alpha-Hydroxylating Monooxygenase (PHM)
J.Am.Chem.Soc. ,
132:15565 - 15572, 2010.(PubMed : 20958070) (DOI: 10.1021/ja103117r)
Experimental method X-RAY DIFFRACTION ( 2.42[Å] )
Other Database Information