English Statistics Help FAQ Contact Us
Download >>

PDBj (Protein Data Bank Japan) maintains a centralized PDB archive of macromolecular structures and provides integrated tools, in collaboration with the RCSB, the BMRB in USA and the PDBe in EU. PDBj is supported by JST-NBDC and Osaka University.

Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

More images...
View in 3D molecule viewer
( jV3 / Jmol ) *1
PDB ID1ev2  sequence information (FASTA format)   
RELATED PDB ID1cvs, 1evt
DescriptorCRYSTAL STRUCTURE OF FGF2 IN COMPLEX WITH THE EXTRACELLULAR LIGAND BINDING DOMAIN OF FGF RECEPTOR 2 (FGFR2)
TitleCRYSTAL STRUCTURE OF FGF2 IN COMPLEX WITH THE EXTRACELLULAR LIGAND BINDING DOMAIN OF FGF RECEPTOR 2 (FGFR2)
Functional KeywordsIMMUNOGLOBULIN (IG)LIKE DOMAINS BELONGING TO THE I-SET SUBGROUP WITHIN IG-LIKE DOMAINS, B-TREFOIL FOLD, GROWTH FACTOR/GROWTH FACTOR RECEPTOR COMPLEX
Biological sourceHomo sapiens (human)
Cellular location [UNP - P21802] Cell membrane; Single-pass type I membrane protein. Isoform 14: Secreted. Isoform 19: Secreted
Organ source [UNP - P21802] Neonatal brain stem
[UNP - P21802] Stomach cancer
[UNP - P21802] Placenta
[UNP - P21802] Mammary gland
[UNP - P21802] Cornea, and Mammary gland
[UNP - P21802] Blood
[UNP - P21802] Brain
Total number of polymer chains8
Total molecular weight159390.8 (the details in Structural Details Page)
AuthorsPlotnikov, A.N. , Hubbard, S.R. , Schlessinger, J. , Mohammadi, M. (deposition date : 2000-04-19, release date : 2000-05-31)
Primary citationPlotnikov, A.N. , Hubbard, S.R. , Schlessinger, J. , Mohammadi, M.
Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity.
Cell(Cambridge,Mass.), 101:413 - 424, 2000.(PubMed : 10830168)  (DOI: 10.1016/S0092-8674(00)80851-X)
Experimental methodX-RAY DIFFRACTION ( 2.20[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P09038, P21802 ) , eF-site , PISA