English Statistics Help FAQ Contact Us
Download >>

PDBj (Protein Data Bank Japan) maintains a centralized PDB archive of macromolecular structures and provides integrated tools, in collaboration with the RCSB, the BMRB in USA and the PDBe in EU. PDBj is supported by JST-NBDC and Osaka University.

Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

More images...
View in 3D molecule viewer
( jV3 / Jmol ) *1
PDB ID1fax  sequence information (FASTA format)   
DescriptorFACTOR XA, (+)-2-[4-[((S)-1-ACETIMIDOYL-3-PYRRODINYL)OXY]-3-(7-AMIDINO-2-NAPTHYL)PROPIONIC ACID
TitleCOAGULATION FACTOR XA INHIBITOR COMPLEX
Functional KeywordsGLYCOPROTEIN, HYDROLASE, SERINE PROTEASE, PLASMA, BLOOD COAGULATION FACTOR, GAMMA-CARBOXYGLUTAMIC ACID, CALCIUM-BINDING
Biological sourceHomo sapiens (human)
Cellular location [UNP - P00742] Secreted
Organ source [UNP - P00742] Ovary
[UNP - P00742] Liver
Total number of polymer chains2
Total molecular weight39411 (the details in Structural Details Page)
AuthorsBrandstetter, H. , Engh, R.A. (deposition date : 1996-08-23, release date : 1997-10-29)
Primary citationBrandstetter, H. , Kuhne, A. , Bode, W. , Huber, R. , von der Saal, W. , Wirthensohn, K. , Engh, R.A.
X-ray structure of active site-inhibited clotting factor Xa. Implications for drug design and substrate recognition.
J.Biol.Chem., 271:29988 - 29992, 1996.(PubMed : 8939944)  (DOI: 10.1074/jbc.271.47.29988)
Experimental methodX-RAY DIFFRACTION ( 3.0[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P00742 ) , eF-site , KEGG ( EC 3.4.21.6 ) , PISA