PDB ID 2b4g sequence information (FASTA format)
Descriptor dihydroorotate dehydrogenase (E.C.1.3.99.11)
Title dihydroorotate dehydrogenase
Functional Keywords STRUCTURAL GENOMICS, PSI, Protein Structure Initiative, Structural Genomics of Pathogenic Protozoa Consortium, SGPP, OXIDOREDUCTASE
Biological source Trypanosoma brucei
Total number of polymer chains 4
Total molecular weight 141592.5 (the details in Structural Details Page )
Authors Arakaki, T.L. , Merritt, E.A. , Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
(deposition date : 2005-09-23, release date : 2005-10-11)
Primary citation Arakaki, T.L. , Buckner, F.S. , Gillespie, J.R. , Malmquist, N.A. , Phillips, M.A. , Kalyuzhniy, O. , Luft, J.R. , Detitta, G.T. , Verlinde, C.L. , Van Voorhis, W.C. , Hol, W.G. , Merritt, E.A. Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies
Mol.Microbiol. ,
68:37 - 50, 2008.(PubMed : 18312275) (DOI: 10.1111/j.1365-2958.2008.06131.x)
Experimental method X-RAY DIFFRACTION ( 1.95[Å] )
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