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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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( jV3 / Jmol ) *1
PDB ID1agc  sequence information (FASTA format)   
DescriptorB*0801, BETA-2 MICROGLOBULIN, HIV-1 GAG PEPTIDE (GGKKKYQL - 7Q MUTATION)
TitleANTAGONIST HIV-1 GAG PEPTIDES INDUCE STRUCTURAL CHANGES IN HLA B8-HIV-1 GAG PEPTIDE (GGKKKYQL-7Q MUTATION)
Functional KeywordsHLA B8, HIV, MHC CLASS I, HISTOCOMPATIBILITY COMPLEX
Biological sourceHomo sapiens (human) ,Human immunodeficiency virus 1 (the details in Structural Details Page)
Cellular location [UNP - P30460] Membrane; Single-pass type I membrane protein
[UNP - P61769] Secreted
Organ source [UNP - P30460] Blood
[UNP - P61769] Peripheral blood
[UNP - P61769] Dendritic cell
[UNP - P61769] Leukemia
[UNP - P61769] Trachea
[UNP - P61769] Eye, and Skin
[UNP - P61769] Urine
Total number of polymer chains3
Total molecular weight44600.7 (the details in Structural Details Page)
AuthorsReid, S.W. , Mcadam, S. , Smith, K.J. , Klenerman, P. , O'Callaghan, C.A. , Harlos, K. , Jakobsen, B.K. , Mcmichael, A.J. , Bell, J. , Stuart, D.I. , Jones, E.Y. (deposition date : 1997-03-24, release date : 1997-06-16)
Primary citationReid, S.W. , McAdam, S. , Smith, K.J. , Klenerman, P. , O'Callaghan, C.A. , Harlos, K. , Jakobsen, B.K. , McMichael, A.J. , Bell, J.I. , Stuart, D.I. , Jones, E.Y.
Antagonist HIV-1 Gag peptides induce structural changes in HLA B8.
J.Exp.Med., 184:2279 - 2286, 1996.(PubMed : 8976183)  (DOI: 10.1084/jem.184.6.2279)
Experimental methodX-RAY DIFFRACTION ( 2.1[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P30460, P61769 ) , eF-site , PISA