PDB ID 1agc sequence information (FASTA format)
Descriptor B*0801, BETA-2 MICROGLOBULIN, HIV-1 GAG PEPTIDE (GGKKKYQL - 7Q MUTATION)
Title ANTAGONIST HIV-1 GAG PEPTIDES INDUCE STRUCTURAL CHANGES IN HLA B8-HIV-1 GAG PEPTIDE (GGKKKYQL-7Q MUTATION)
Functional Keywords HLA B8, HIV, MHC CLASS I, HISTOCOMPATIBILITY COMPLEX
Biological source Homo sapiens
(human)
,Human immunodeficiency virus 1
(the details in Structural Details Page )
Cellular location
[UNP - P30460 ]
Membrane; Single-pass type I membrane protein
[UNP - P61769 ]
Secreted
Organ source
[UNP - P30460 ]
Blood
[UNP - P61769 ]
Peripheral blood
[UNP - P61769 ]
Dendritic cell
[UNP - P61769 ]
Leukemia
[UNP - P61769 ]
Trachea
[UNP - P61769 ]
Eye, and Skin
[UNP - P61769 ]
Urine
Total number of polymer chains 3
Total molecular weight 44600.7 (the details in Structural Details Page )
Authors Reid, S.W. , Mcadam, S. , Smith, K.J. , Klenerman, P. , O'Callaghan, C.A. , Harlos, K. , Jakobsen, B.K. , Mcmichael, A.J. , Bell, J. , Stuart, D.I. , Jones, E.Y.
(deposition date : 1997-03-24, release date : 1997-06-16)
Primary citation Reid, S.W. , McAdam, S. , Smith, K.J. , Klenerman, P. , O'Callaghan, C.A. , Harlos, K. , Jakobsen, B.K. , McMichael, A.J. , Bell, J.I. , Stuart, D.I. , Jones, E.Y. Antagonist HIV-1 Gag peptides induce structural changes in HLA B8.
J.Exp.Med. ,
184:2279 - 2286, 1996.(PubMed : 8976183) (DOI: 10.1084/jem.184.6.2279)
Experimental method X-RAY DIFFRACTION ( 2.1[Å] )
Other Database Information