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<Asymmetric unit>

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PDB ID1fv3  sequence information (FASTA format)   
RELATED PDB ID1d0h, 1dll, 1diw, 1dfq, 1af9, 1a8d, 1fv2
DescriptorTETANUS TOXIN HEAVY CHAIN
TitleTHE HC FRAGMENT OF TETANUS TOXIN COMPLEXED WITH AN ANALOGUE OF ITS GANGLIOSIDE RECEPTOR GT1B
Functional Keywordstoxin, carbohydrate, ganglioside, multi-valent binding, receptor
TOXIN
Biological sourceClostridium tetani
Total number of polymer chains4
Total molecular weight111459.2 (the details in Structural Details Page)
AuthorsFotinou, C. , Emsley, P. , Black, I. , Ando, H. , Ishida, H. , Kiso, M. , Sinha, K.A. , Fairweather, N.F. , Isaacs, N.W. (deposition date : 2000-09-18, release date : 2001-09-05)
Primary citationFotinou, C. , Emsley, P. , Black, I. , Ando, H. , Ishida, H. , Kiso, M. , Sinha, K.A. , Fairweather, N.F. , Isaacs, N.W.
The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin.
J.Biol.Chem., 276:32274 - 32281, 2001.(PubMed : 11418600)  (DOI: 10.1074/jbc.M103285200)
Experimental methodX-RAY DIFFRACTION ( 2.30[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P04958 ) , eF-site , PISA