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Summary [1fvv]

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PDB ID or Keywordsequenceauthor name

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<Asymmetric unit> More images... View in 3D molecule viewer ( jV3 / Jmol ) *1 <Biological unit> View in 3D molecule viewer ( jV3 ) *1

PDB ID 1fvv  sequence information (FASTA format)    Descriptor CELL DIVISION PROTEIN KINASE 2 (E.C.2.7.1.37)/CYCLIN A Title THE STRUCTURE OF CDK2/CYCLIN A IN COMPLEX WITH AN OXINDOLE INHIBITOR Functional Keywords cyclin-dependent kinase, cyclin A, TRANSFERASE, CELL CYCLE Biological source Homo sapiens (human) Cellular location [UNP - P20248] Nucleus Organ source [UNP - P24941] Placenta [UNP - P24941] Epithelium [UNP - P24941] Lung [UNP - P20248] Brain Total number of polymer chains 4 Total molecular weight 128588 (the details in Structural Details Page) Authors Davis, S.T. , Benson, B.G. , Bramson, H.N. , Chapman, D.E. , Dickerson, S.H. , Dold, K.M. , Eberwein, D.J. , Edelstein, M. , Frye, S.V. , Gampe Jr., R.T. , Griffin, R.J. , Harris, P.A. , Hassell, A.M. , Holmes, W.D. , Hunter, R.N. , Knick, V.B. , Lackey, K. , Lovejoy, B. , Luzzio, M.J. , Murray, D. , Parker, P. , Rocque, W.J. , Shewchuk, L. , Veal, J.M. , Walker, D.H. , Kuyper, L.K. (deposition date : 2000-09-20, release date : 2001-01-17) Primary citation Davis, S.T. , Benson, B.G. , Bramson, H.N. , Chapman, D.E. , Dickerson, S.H. , Dold, K.M. , Eberwein, D.J. , Edelstein, M. , Frye, S.V. , Gampe Jr, R.T. , Griffin, R.J. , Harris, P.A. , Hassell, A.M. , Holmes, W.D. , Hunter, R.N. , Knick, V.B. , Lackey, K. , Lovejoy, B. , Luzzio, M.J. , Murray, D. , Parker, P. , Rocque, W.J. , Shewchuk, L. , Veal, J.M. , Walker, D.H. , Kuyper, L.F. Prevention of chemotherapy-induced alopecia in rats by CDK inhibitors. Science, 291:134 - 137, 2001.(PubMed : 11141566)  (DOI: 10.1126/science.291.5501.134) Experimental method X-RAY DIFFRACTION ( 2.80[Å] ) Other Database Information EM Navigator , Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P24941, P20248 ) , eF-site , KEGG ( EC 2.7.1.37 ) , GDB , ProTherm , EzCatDB , PISA , PQS

Electron density map is available to be displayed.

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