PDB ID 2c6t sequence information (FASTA format)
RELATED PDB ID 1aq1 , 1b38 , 1b39 , 1buh , 1ckp , 1di8 , 1dm2 , 1e1v , 1e1x , 1e9h , 1f5q , 1fin , 1fq1 , 1fvt , 1fvv , 1g5s , 1gih , 1gii , 1gij , 1gy3 , 1gz8 , 1h00 , 1h01 , 1h07 , 1h08 , 1h0v , 1h0w , 1h1p , 1h1q , 1h1r , 1h1s , 1h24 , 1h25 , 1h26 , 1h27 , 1h28 , 1hck , 1hcl , 1jst , 1jsu , 1jsv , 1jvp , 1ke5 , 1ke6 , 1ke7 , 1ke8 , 1ke9 , 1ogu , 1oi9 , 1oiq , 1oir , 1oit , 1oiu , 1oiy , 1oku , 1okv , 1okw , 1ol1 , 1ol2 , 1p2a , 1p5e , 1pf8 , 1pkd , 1pw2 , 1pxi , 1pxj , 1pxk , 1pxl , 1pxm , 1pxn , 1pxo , 1pxp , 1pye , 1qmz , 1r78 , 1urc , 1urw , 1v1k , 1vyw , 1vyz , 1w0x , 1w8c , 1w98 , 1wcc , 1y8y , 1y91 , 2b52 , 2b53 , 2b54 , 2b55 , 2bhe , 2bhh , 2bkz , 2bpm , 2btr , 2bts , 2c4g , 2c5n , 2c5o , 2c5p , 2c5t , 2c5v , 2c5x , 2c5y , 2c68 , 2c69 , 2c6i , 2c6k
Descriptor CELL DIVISION PROTEIN KINASE 2 (E.C.2.7.1.37), CYCLIN A2
Title CRYSTAL STRUCTURE OF THE HUMAN CDK2 COMPLEXED WITH THE TRIAZOLOPYRIMIDINE INHIBITOR
Functional Keywords SERINE/THREONINE PROTEIN KINASE, CDK2, ATP-BINDING, CELL CYCLE, MITOSIS, PHOSPHORYLATION, TRIAZOLOPYRIMIDINE INHIBITOR, COMPLEX (TRANSFERASE/CYCLIN2)
Biological source HOMO SAPIENS
(HUMAN)
Cellular location
[UNP - P20248 ]
Nucleus
Organ source
[UNP - P24941 ]
PlacentaUNP - P24941 ]
EpitheliumUNP - P24941 ]
LungUNP - P20248 ]
Brain
Total number of polymer chains 4
Total molecular weight 128139.4 (the details in Structural Details Page )
Authors Richardson, C.M. , Dokurno, P. , Murray, J.B. , Surgenor, A.E.
(deposition date : 2005-11-11, release date : 2005-12-07)
Primary citation Richardson, C.M. , Williamson, D.S. , Parratt, M.J. , Borgognoni, J. , Cansfield, A.D. , Dokurno, P. , Francis, G.L. , Howes, R. , Moore, J.D. , Murray, J.B. , Robertson, A. , Surgenor, A.E. , Torrance, C.J.Bioorg.Med.Chem.Lett. ,
16:1353 - , 2006.(PubMed : 16325401) (DOI: 10.1016/J.BMCL.2005.11.048)
Experimental method X-RAY DIFFRACTION ( 2.61[Å] )
Other Database Information
