Gene information | Cerebellar Development Transcriptome Database (CDT-DB)

20436479 A genomic atlas of mouse hypothalamic development
20181579 The progenitor zone of the ventral medial ganglionic eminence requires Nkx2-1 to generate most of the globus pallidus but few neocortical interneurons
20081190 Domain-specific control of neurogenesis achieved through patterned regulation of Notch ligand expression
19842188 Fzd3 and Fzd6 deficiency results in a severe midbrain morphogenesis defect
19780901 Vesicular monoamine transporter 2 and dopamine transporter are molecular targets of Pitx3 in the ventral midbrain dopamine neurons

Show all (10) references (detailed information)

CD gene Number	CD22583
Gene Symbol	Nkx6-2
Gene description	NK6 homeobox 2
Alternative name(s)	NK6 transcription factor related, locus 2 (Drosophila); NK6 transcription factor related, locus 2; OTTMUSP00000029317; glial and testis specific homeobox; Drosophila NK transcription factor related, gene family 6, locus 2
Alternative name(s)	Gtx, Nkx6.2
Accession ID	NM_183248
Gene Category
Gene Ontology	biological_process cell differentiation , endocrine pancreas development , myelination in the central nervous system , negative regulation of cell fate commitment , negative regulation of glial cell differentiation , negative regulation of transcription from RNA polymerase II promoter , neuromuscular process controlling balance , oligodendrocyte differentiation , positive regulation of cell fate commitment , positive regulation of glial cell differentiation , regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification , regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification ... [Show All] cellular_component nucleus molecular_function sequence-specific DNA binding , transcription factor activity
Temporal expression	up-and-down regulation
Spatial expression (characteristic site)	P7 : P21 :
Brain distribution (characteristic site)	P7 : P21 :
Brain specificity
Experimental data	Temporal Tissue
Probe	CDT EST : Affymetrix : 1427420_at (MG 430 2.0 Array)
Links	General information Entrez Gene : 14912 MGI : 1352738 Ensembl : ENSMUSG00000041309 UniGene : Mm.28308, Mm.476889, Mm.478720 OMIM : 605955 GEO : Nkx6-2 KEGG : Genome information Harvester UCSC Mouse Genome Browser Gateway Perlegen/NIEHS Mouse Genome Browser Functional genomics GeneNetwork Mouse Phenome Database BioGPS STRING Nervous system SynDB Mouse Neuronal Expression Database Reference information GoPubMed iHOP PubMed Spatial information ABA GenePaint BGEM
References	20436479 A genomic atlas of mouse hypothalamic development 20181579 The progenitor zone of the ventral medial ganglionic eminence requires Nkx2-1 to generate most of the globus pallidus but few neocortical interneurons 20081190 Domain-specific control of neurogenesis achieved through patterned regulation of Notch ligand expression 19842188 Fzd3 and Fzd6 deficiency results in a severe midbrain morphogenesis defect 19780901 Vesicular monoamine transporter 2 and dopamine transporter are molecular targets of Pitx3 in the ventral midbrain dopamine neurons Show all (10) references (detailed information)