Gene information
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CD gene Number CD09290 
Gene Symbol Ctbp2     
Gene description C-terminal binding protein 2 
Alternative name(s) C-terminal-binding protein 2; gene trap ROSA b-geo 6 
Ribeye, Gtrgeo6, AA407280, D7Ertd45e 
Accession ID NM_001170744 ,  NM_009980  
Gene Category  
Gene Ontology biological_process
cell differentiation , metabolic process , negative regulation of transcription, DNA-dependent , oxidation reduction , regulation of transcription , transcription , white fat cell differentiation ... [Show All]

cellular_component
cell junction , nucleus , synapse , transcriptional repressor complex

molecular_function
binding , catalytic activity , cofactor binding , NAD or NADH binding , oxidoreductase activity , oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor , protein binding , transcription corepressor activity , transcription repressor activity ... [Show All]

Temporal expression pending  
Spatial expression (characteristic site) P7 :
P21 :
Brain distribution (characteristic site) P7 :
P21 :
Brain specificity  
Experimental data Temporal Temporal information Tissue Tissue information  
Probe CDT EST :  
Affymetrix : 1434705_at (MG 430 2.0 Array)
Links General information
Entrez Gene : 13017
MGI : 1201686
Ensembl : ENSMUSG00000030970
UniGene : Mm.246240, Mm.389984
OMIM : 602619
GEO : Ctbp2
KEGG : Chronic myeloid leukemia 05220, Notch signaling pathway 04330, Pathways in cancer 05200, Wnt signaling pathway 04310
Genome information
Harvester
UCSC Mouse Genome Browser Gateway
Perlegen/NIEHS Mouse Genome Browser
Functional genomics
GeneNetwork
Mouse Phenome Database
BioGPS
STRING
Nervous system
SynDB
Mouse Neuronal Expression Database
Reference information
GoPubMed
iHOP
PubMed
Spatial information
ABA
GenePaint
BGEM
References

  • 19945391 DSCAM and DSCAML1 function in self-avoidance in multiple cell types in the developing mouse retina
  • 19825414 Delayed differentiation in embryonic stem cells and mesodermal progenitors in the absence of CtBP2
  • 19564408 C/EBPalpha and the corepressors CtBP1 and CtBP2 regulate repression of select visceral white adipose genes during induction of the brown phenotype in white adipocytes by peroxisome proliferator-activated receptor gamma agonists
  • 19515997 Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation
  • 19181930 The transcription repressor, ZEB1, cooperates with CtBP2 and HDAC1 to suppress IL-2 gene activation in T cells
Show all (10) references (detailed information)


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