CD00148

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD00148

CD00148

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Faf1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• Fas-associated factor 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• Fas-associated factor 1
• FAS-associated factor 1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Dffrx
• AA408698
• Fam

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/14084

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• Fas-associated factor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:109419

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_007983

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000010517

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.318259

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=604460

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• K. Araki, et.al., Exchangeable gene trap using the Cre/mutated lox system., Cellular and molecular biology (Noisy-le-Grand, France), 1999, 45
  http://rdf.ncbi.nlm.nih.gov/pubmed/10512203
• N. Kikyo, et.al., Mapping of the Fas-associated factor 1 gene, Faf1, to mouse chromosome 4C6 by FISH., Mammalian genome : official journal of the International Mammalian Genome Society, 1997, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/9069128
• S A. Wood, et.al., Cloning and expression analysis of a novel mouse gene with sequence similarity to the Drosophila fat facets gene., Mechanisms of development, 1997, 63
  http://rdf.ncbi.nlm.nih.gov/pubmed/9178254
• D. Obradović, et.al., DAXX, FLASH, and FAF-1 modulate mineralocorticoid and glucocorticoid receptor-mediated transcription in hippocampal cells--toward a basis for the opposite actions elicited by two nuclear receptors?, Molecular pharmacology, 2004, 65
  http://rdf.ncbi.nlm.nih.gov/pubmed/14978255
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Moon-Sun. Jang, et.al., Negative feedback regulation of Aurora-A via phosphorylation of Fas-associated factor-1., The Journal of biological chemistry, 2008, 283
  http://rdf.ncbi.nlm.nih.gov/pubmed/18790738
• D. De Zio, et.al., Faf1 is expressed during neurodevelopment and is involved in Apaf1-dependent caspase-3 activation in proneural cells., Cellular and molecular life sciences : CMLS, 2008, 65
  http://rdf.ncbi.nlm.nih.gov/pubmed/18480964
• Amiya K. Ghosh, et.al., Fas-associated factor 1 is a negative regulator in capsaicin induced cancer cell apoptosis., Cancer letters, 2010, 287
  http://rdf.ncbi.nlm.nih.gov/pubmed/19570606
• Ibrahim M. Adham, et.al., Fas-associated factor (FAF1) is required for the early cleavage-stages of mouse embryo., Molecular human reproduction, 2008, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/18303090
• Seung-Wook. Ryu, et.al., Fas-associated factor 1, FAF1, is a member of Fas death-inducing signaling complex., The Journal of biological chemistry, 2003, 278
  http://rdf.ncbi.nlm.nih.gov/pubmed/12702723
• K. Chu, et.al., A Fas-associated protein factor, FAF1, potentiates Fas-mediated apoptosis., Proceedings of the National Academy of Sciences of the United States of America, 1995, 92
  http://rdf.ncbi.nlm.nih.gov/pubmed/8524870
• G M. Brown, et.al., Characterisation of the coding sequence and fine mapping of the human DFFRY gene and comparative expression analysis and mapping to the Sxrb interval of the mouse Y chromosome of the Dffry gene., Human molecular genetics, 1998, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/9384609

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• protein kinase binding
  http://purl.obolibrary.org/obo/GO_0019901
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• positive regulation of protein complex assembly
  http://purl.obolibrary.org/obo/GO_0031334
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• regulation of protein catabolic process
  http://purl.obolibrary.org/obo/GO_0042176
• cell death
  http://purl.obolibrary.org/obo/GO_0008219
• cytoplasmic sequestering of NF-kappaB
  http://purl.obolibrary.org/obo/GO_0007253
• perinuclear region of cytoplasm
  http://purl.obolibrary.org/obo/GO_0048471
• ubiquitin binding
  http://purl.obolibrary.org/obo/GO_0043130
• regulation of cell adhesion
  http://purl.obolibrary.org/obo/GO_0030155
• ubiquitin protein ligase binding
  http://purl.obolibrary.org/obo/GO_0031625
• nuclear envelope
  http://purl.obolibrary.org/obo/GO_0005635
• protein domain specific binding
  http://purl.obolibrary.org/obo/GO_0019904
• apoptotic process
  http://purl.obolibrary.org/obo/GO_0006915
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• positive regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0043065
• NF-kappaB binding
  http://purl.obolibrary.org/obo/GO_0051059
• Cdc48p-Npl4p-Ufd1p AAA ATPase complex
  http://purl.obolibrary.org/obo/GO_0034098
• heat shock protein binding
  http://purl.obolibrary.org/obo/GO_0031072

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName