CD00215

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD00215

CD00215

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Nfkb1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• nuclear factor-kappaB p50
• nuclear factor NF-kappa-B p105 subunit
• NF-kappa-B1 p84/NF-kappa-B1 p98
• nuclear factor of kappa light chain gene enhancer in B-cells 1, p105
• DNA-binding factor KBF1
• EBP-1
• p50 subunit of NF-kappaB
• nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• nuclear factor kappaB p50
• NF-kappaB1
• p50 subunit of NF kappaB
• p50
• NF-KB1
• p50/p105
• NF kappaB1
• p105
• NF-kappaB p50
• NF-kappaB

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/18033

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
  http://metadb.riken.jp/db/mgi_rdf/MGI:97312

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_008689

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000028163

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.256765

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=164011

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Zhongxin. Lu, et.al., miR-301a as an NF-κB activator in pancreatic cancer cells., The EMBO journal, 2011, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/21113131
• Huei-Ting. Yang, et.al., NF-κB1 inhibits TLR-induced IFN-β production in macrophages through TPL-2-dependent ERK activation., Journal of immunology (Baltimore, Md. : 1950), 2011, 186
  http://rdf.ncbi.nlm.nih.gov/pubmed/21217011
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Dinis Pedro. Calado, et.al., Constitutive canonical NF-κB activation cooperates with disruption of BLIMP1 in the pathogenesis of activated B cell-like diffuse large cell lymphoma., Cancer cell, 2010, 18
  http://rdf.ncbi.nlm.nih.gov/pubmed/21156282
• R P. Ryseck, et.al., RelB, a new Rel family transcription activator that can interact with p50-NF-kappa B., Molecular and cellular biology, 1992, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/1732739
• F G. Wulczyn, et.al., Candidate proto-oncogene bcl-3 encodes a subunit-specific inhibitor of transcription factor NF-kappa B., Nature, 1992, 358
  http://rdf.ncbi.nlm.nih.gov/pubmed/1501714
• S. Ghosh, et.al., Cloning of the p50 DNA binding subunit of NF-kappa B: homology to rel and dorsal., Cell, 1990, 62
  http://rdf.ncbi.nlm.nih.gov/pubmed/2203532
• Jian. Liang, et.al., MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-kappaB signaling., The Journal of experimental medicine, 2010, 207
  http://rdf.ncbi.nlm.nih.gov/pubmed/21115689
• G P. Nolan, et.al., DNA binding and I kappa B inhibition of the cloned p65 subunit of NF-kappa B, a rel-related polypeptide., Cell, 1991, 64
  http://rdf.ncbi.nlm.nih.gov/pubmed/2001591
• J. Inoue, et.al., I kappa B gamma, a 70 kd protein identical to the C-terminal half of p110 NF-kappa B: a new member of the I kappa B family., Cell, 1992, 68
  http://rdf.ncbi.nlm.nih.gov/pubmed/1339305

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• negative regulation of cytokine production
  http://purl.obolibrary.org/obo/GO_0001818
• signal transduction
  http://purl.obolibrary.org/obo/GO_0007165
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• apoptotic process
  http://purl.obolibrary.org/obo/GO_0006915
• negative regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0000122
• macromolecular complex
  http://purl.obolibrary.org/obo/GO_0032991
• regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006355
• positive regulation of canonical Wnt signaling pathway
  http://purl.obolibrary.org/obo/GO_0090263
• sequence-specific DNA binding
  http://purl.obolibrary.org/obo/GO_0043565
• transcription regulatory region sequence-specific DNA binding
  http://purl.obolibrary.org/obo/GO_0000976
• sequence-specific DNA binding transcription factor activity
  http://purl.obolibrary.org/obo/GO_0003700
• mitochondrion
  http://purl.obolibrary.org/obo/GO_0005739
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• positive regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0045893
• positive regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0045944
• double-stranded DNA binding
  http://purl.obolibrary.org/obo/GO_0003690
• negative regulation of calcidiol 1-monooxygenase activity
  http://purl.obolibrary.org/obo/GO_0010956
• negative regulation of interleukin-12 biosynthetic process
  http://purl.obolibrary.org/obo/GO_0045083
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• heat shock protein binding
  http://purl.obolibrary.org/obo/GO_0031072
• negative regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0043066
• DNA binding
  http://purl.obolibrary.org/obo/GO_0003677
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• transcription regulatory region DNA binding
  http://purl.obolibrary.org/obo/GO_0044212
• negative regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0045892
• response to oxidative stress
  http://purl.obolibrary.org/obo/GO_0006979
• protein homodimerization activity
  http://purl.obolibrary.org/obo/GO_0042803
• transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006351
• lymph node development
  http://purl.obolibrary.org/obo/GO_0048535

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04662
• http://www.genome.jp/dbget-bin/www_bget?map05164
• http://www.genome.jp/dbget-bin/www_bget?map05132
• http://www.genome.jp/dbget-bin/www_bget?map05220
• http://www.genome.jp/dbget-bin/www_bget?map05133
• http://www.genome.jp/dbget-bin/www_bget?map04620
• http://www.genome.jp/dbget-bin/www_bget?map05215
• http://www.genome.jp/dbget-bin/www_bget?map04660
• http://www.genome.jp/dbget-bin/www_bget?map04210
• http://www.genome.jp/dbget-bin/www_bget?map05200
• http://www.genome.jp/dbget-bin/www_bget?map05145
• http://www.genome.jp/dbget-bin/www_bget?map04623
• http://www.genome.jp/dbget-bin/www_bget?map05162
• http://www.genome.jp/dbget-bin/www_bget?map05221
• http://www.genome.jp/dbget-bin/www_bget?map05168
• http://www.genome.jp/dbget-bin/www_bget?map05134
• http://www.genome.jp/dbget-bin/www_bget?map04010
• http://www.genome.jp/dbget-bin/www_bget?map05212
• http://www.genome.jp/dbget-bin/www_bget?map04380
• http://www.genome.jp/dbget-bin/www_bget?map04621
• http://www.genome.jp/dbget-bin/www_bget?map04062
• http://www.genome.jp/dbget-bin/www_bget?map04722
• http://www.genome.jp/dbget-bin/www_bget?map04920
• http://www.genome.jp/dbget-bin/www_bget?map05142
• http://www.genome.jp/dbget-bin/www_bget?map05146
• http://www.genome.jp/dbget-bin/www_bget?map05202
• http://www.genome.jp/dbget-bin/www_bget?map05140
• http://www.genome.jp/dbget-bin/www_bget?map05166
• http://www.genome.jp/dbget-bin/www_bget?map04622
• http://www.genome.jp/dbget-bin/www_bget?map05152
• http://www.genome.jp/dbget-bin/www_bget?map05160
• http://www.genome.jp/dbget-bin/www_bget?map05222

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Salmonella infection
• Pathways in cancer
• Influenza A
• Transcriptional misregulation in cancers
• Acute myeloid leukemia
• Prostate cancer
• Legionellosis
• Toll-like receptor signaling pathway
• Chagas disease (American trypanosomiasis)
• Chronic myeloid leukemia
• Adipocytokine signaling pathway
• Small cell lung cancer
• MAPK signaling pathway
• Cytosolic DNA-sensing pathway
• Pertussis
• Osteoclast differentiation
• Pancreatic cancer
• Apoptosis
• T cell receptor signaling pathway
• Herpes simplex infection
• Chemokine signaling pathway
• B cell receptor signaling pathway
• Measles
• Tuberculosis
• NOD-like receptor signaling pathway
• Neurotrophin signaling pathway
• Leishmaniasis
• RIG-I-like receptor signaling pathway
• Amoebiasis
• Toxoplasmosis
• HTLV-I infection
• Hepatitis C