CD00490

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD00490

CD00490

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Msra

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• methionine sulfoxide reductase A

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• peptide-methionine (S)-S-oxide reductase
• peptide Met(O) reductase
• mitochondrial peptide methionine sulfoxide reductase
• PMSR
• methionine sulfoxide reductase A
• protein-methionine-S-oxide reductase
• peptide methionine sulfoxide reductase

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• 6530413P12Rik
• MSR-A
• 2310045J23Rik

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/110265

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• methionine sulfoxide reductase A
  http://metadb.riken.jp/db/mgi_rdf/MGI:106916

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001253715
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001253712
• https://www.ncbi.nlm.nih.gov/nuccore/NM_026322
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001253716
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001253714

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000054733

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.26713

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=601250

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Chi. Zhang, et.al., Methionine sulfoxide reductase A (MsrA) protects cultured mouse embryonic stem cells from H2O2-mediated oxidative stress., Journal of cellular biochemistry, 2010, 111
  http://rdf.ncbi.nlm.nih.gov/pubmed/20506347
• Hwa-Young. Kim, et.al., Role of structural and functional elements of mouse methionine-S-sulfoxide reductase in its subcellular distribution., Biochemistry, 2005, 44
  http://rdf.ncbi.nlm.nih.gov/pubmed/15924425
• J. Moskovitz, et.al., Methionine sulfoxide reductase (MsrA) is a regulator of antioxidant defense and lifespan in mammals., Proceedings of the National Academy of Sciences of the United States of America, 2001, 98
  http://rdf.ncbi.nlm.nih.gov/pubmed/11606777
• J. Bilsborough, et.al., Identification of a second major tumor-specific antigen recognized by CTLs on mouse mastocytoma P815., Journal of immunology (Baltimore, Md. : 1950), 1999, 162
  http://rdf.ncbi.nlm.nih.gov/pubmed/10092811
• Derek B. Oien, et.al., Dopamine D(2) receptor function is compromised in the brain of the methionine sulfoxide reductase A knockout mouse., Journal of neurochemistry, 2010, 114
  http://rdf.ncbi.nlm.nih.gov/pubmed/20374422
• Jackob. Moskovitz, et.al., Selenium-deficient diet enhances protein oxidation and affects methionine sulfoxide reductase (MsrB) protein level in certain mouse tissues., Proceedings of the National Academy of Sciences of the United States of America, 2003, 100
  http://rdf.ncbi.nlm.nih.gov/pubmed/12792026
• Changlong. Nan, et.al., Deficiency of methionine sulfoxide reductase A causes cellular dysfunction and mitochondrial damage in cardiac myocytes under physical and oxidative stresses., Biochemical and biophysical research communications, 2010, 402
  http://rdf.ncbi.nlm.nih.gov/pubmed/20971073
• Nelson B. Cole, et.al., Oxidative stress causes reversible changes in mitochondrial permeability and structure., Experimental gerontology, 2010, 45
  http://rdf.ncbi.nlm.nih.gov/pubmed/20096768
• J. Moskovitz, et.al., Chromosomal localization of the mammalian peptide-methionine sulfoxide reductase gene and its differential expression in various tissues., Proceedings of the National Academy of Sciences of the United States of America, 1996, 93
  http://rdf.ncbi.nlm.nih.gov/pubmed/8622914
• Geumsoo. Kim, et.al., Dual sites of protein initiation control the localization and myristoylation of methionine sulfoxide reductase A., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20368336

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• oxidation-reduction process
  http://purl.obolibrary.org/obo/GO_0055114
• protein metabolic process
  http://purl.obolibrary.org/obo/GO_0019538
• aging
  http://purl.obolibrary.org/obo/GO_0007568
• peptide-methionine (S)-S-oxide reductase activity
  http://purl.obolibrary.org/obo/GO_0008113
• oxidoreductase activity
  http://purl.obolibrary.org/obo/GO_0016491
• oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
  http://purl.obolibrary.org/obo/GO_0016671
• mitochondrion
  http://purl.obolibrary.org/obo/GO_0005739

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName