CD00754

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD00754

CD00754

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Huwe1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• HECT, UBA and WWE domain containing 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• E3 ubiquitin-protein ligase HUWE1
• HECT, UBA and WWE domain containing 1
• URE-binding protein 1
• upstream regulatory element-binding protein 1
• upstream regulatory element binding protein 1
• Mcl-1 ubiquitin ligase
• E3Histone
• HECT, UBA and WWE domain-containing protein 1
• URE-B1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Gm1718
• LASU1
• Ib772
• 5430439H10Rik
• C430014N20Rik
• AU041296
• mKIAA0312
• Mule
• C80292
• Ureb1
• Arf-bp1
• LOC382250

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/59026

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• HECT, UBA and WWE domain containing 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1926884

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_021523

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000025261

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.27372

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=300697

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Brian J. Cox, et.al., Phenotypic annotation of the mouse X chromosome., Genome research, 2010, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/20548051
• Bryan A. Ballif, et.al., Phosphoproteomic analysis of the developing mouse brain., Molecular & cellular proteomics : MCP, 2004, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/15345747
• Doug. Stryke, et.al., BayGenomics: a resource of insertional mutations in mouse embryonic stem cells., Nucleic acids research, 2003, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/12520002
• Noriko. Okazaki, et.al., Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries., DNA research : an international journal for rapid publication of reports on genes and genomes, 2002, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/12465718
• K D. Tsuchiya, et.al., Chromosomal domains and escape from X inactivation: comparative X inactivation analysis in mouse and human., Mammalian genome : official journal of the International Mammalian Genome Society, 2000, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/11003698
• Lei. Yin, et.al., E3 ligases Arf-bp1 and Pam mediate lithium-stimulated degradation of the circadian heme receptor Rev-erb alpha., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20534529
• Domenico. D'Arca, et.al., Huwe1 ubiquitin ligase is essential to synchronize neuronal and glial differentiation in the developing cerebellum., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20231446
• Yi. Yang, et.al., E3 ubiquitin ligase Mule ubiquitinates Miz1 and is required for TNFalpha-induced JNK activation., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20624960
• Y. Piao, et.al., Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method., Genome research, 2001, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/11544199
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• DNA binding
  http://purl.obolibrary.org/obo/GO_0003677
• ubiquitin-dependent protein catabolic process
  http://purl.obolibrary.org/obo/GO_0006511
• cellular response to DNA damage stimulus
  http://purl.obolibrary.org/obo/GO_0006974
• cell differentiation
  http://purl.obolibrary.org/obo/GO_0030154
• binding
  http://purl.obolibrary.org/obo/GO_0005488
• ligase activity
  http://purl.obolibrary.org/obo/GO_0016874
• protein monoubiquitination
  http://purl.obolibrary.org/obo/GO_0006513
• acid-amino acid ligase activity
  http://purl.obolibrary.org/obo/GO_0016881
• base-excision repair
  http://purl.obolibrary.org/obo/GO_0006284
• intracellular
  http://purl.obolibrary.org/obo/GO_0005622
• protein polyubiquitination
  http://purl.obolibrary.org/obo/GO_0000209
• cellular protein modification process
  http://purl.obolibrary.org/obo/GO_0006464
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• histone ubiquitination
  http://purl.obolibrary.org/obo/GO_0016574
• protein modification process
  http://purl.obolibrary.org/obo/GO_0036211
• DNA repair
  http://purl.obolibrary.org/obo/GO_0006281

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04120

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Ubiquitin mediated proteolysis