CD00977

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD00977

CD00977

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Tle4

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• transducin-like enhancer of split 4, homolog of Drosophila E(spl)

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• transducin-like enhancer protein 4
• B lymphocyte gene 1
• grg-4
• transducin-like enhancer of split 4, homolog of Drosophila E(spl)
• groucho-related protein 4

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• ESG
• ESTM13
• Bce1
• ESP2
• Bce-1
• ESG4
• ESTM14
• X83332
• AA792082
• Grg4
• 5730411M05Rik
• X83333
• E(spI)

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/21888

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• transducin-like enhancer of split 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:104633

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_011600

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000024642

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.103638

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=605132

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• K E. Koop, et.al., Transcripts of Grg4, a murine groucho-related gene, are detected in adjacent tissues to other murine neurogenic gene homologues during embryonic development., Mechanisms of development, 1996, 59
  http://rdf.ncbi.nlm.nih.gov/pubmed/8892234
• G. Dehni, et.al., TLE expression correlates with mouse embryonic segmentation, neurogenesis, and epithelial determination., Mechanisms of development, 1995, 53
  http://rdf.ncbi.nlm.nih.gov/pubmed/8645603
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Francesco. Bedogni, et.al., Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20615956
• Noelia. Urbán, et.al., Nolz1 promotes striatal neurogenesis through the regulation of retinoic acid signaling., Neural development, 2010, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/20735826
• M. Mallo, et.al., Protein characterization and targeted disruption of Grg, a mouse gene related to the groucho transcript of the Drosophila Enhancer of split complex., Developmental dynamics : an official publication of the American Association of Anatomists, 1995, 204
  http://rdf.ncbi.nlm.nih.gov/pubmed/8573724
• Shigetoshi. Yokoyama, et.al., A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58., Developmental cell, 2009, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/20059953
• Chrissandra J. Zagami, et.al., Molecular characterization of the mouse superior lateral parabrachial nucleus through expression of the transcription factor Runx1., PloS one, 2010, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/21085653
• C. Leon, et.al., Grg3, a murine Groucho-related gene, is expressed in the developing nervous system and in mesenchyme-induced epithelial structures., Developmental dynamics : an official publication of the American Association of Anatomists, 1997, 208
  http://rdf.ncbi.nlm.nih.gov/pubmed/8989517
• V T. Tchernev, et.al., Genetic mapping of 20 novel expressed sequence tags from midgestation mouse embryos suggests chromosomal clustering., Genomics, 1997, 40
  http://rdf.ncbi.nlm.nih.gov/pubmed/9070936

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• transcription corepressor activity
  http://purl.obolibrary.org/obo/GO_0003714
• negative regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0045892
• transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006351
• chromatin binding
  http://purl.obolibrary.org/obo/GO_0003682
• regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0006357
• negative regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0000122
• Wnt signaling pathway
  http://purl.obolibrary.org/obo/GO_0016055
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006355
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
  http://purl.obolibrary.org/obo/GO_0003705
• regulation of RNA biosynthetic process
  http://purl.obolibrary.org/obo/GO_2001141
• repressing transcription factor binding
  http://purl.obolibrary.org/obo/GO_0070491

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName