CD01085

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD01085

CD01085

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Hipk3

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• homeodomain interacting protein kinase 3

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• homeodomain-interacting protein kinase 3
• HCMV-interacting protein
• FIST
• nuclear body-associated kinase 3
• androgen receptor-interacting nuclear protein kinase
• homeodomain interacting protein kinase 3
• nbak3
• ANPK
• fas-interacting serine/threonine-protein kinase

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• ANPK
• Nbak3
• PKY
• YAK1
• FIST3
• DYRK6

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/15259

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• homeodomain interacting protein kinase 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1314882

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_010434
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001145824

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000027177

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.257925

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=604424

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• A M. Moilanen, et.al., Activation of androgen receptor function by a novel nuclear protein kinase., Molecular biology of the cell, 1998, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/9725910
• Y H. Kim, et.al., Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors., The Journal of biological chemistry, 1998, 273
  http://rdf.ncbi.nlm.nih.gov/pubmed/9748262
• Peter J. Bailey, et.al., A global genomic transcriptional code associated with CNS-expressed genes., Experimental cell research, 2006, 312
  http://rdf.ncbi.nlm.nih.gov/pubmed/16919269
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Toshihiro. Inoue, et.al., Involvement of the Hipk family in regulation of eyeball size, lens formation and retinal morphogenesis., FEBS letters, 2010, 584
  http://rdf.ncbi.nlm.nih.gov/pubmed/20579985
• Oscar L. Sierra, et.al., Runx2 trans-activation mediated by the MSX2-interacting nuclear target requires homeodomain interacting protein kinase-3., Molecular endocrinology (Baltimore, Md.), 2010, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/20484411
• K. Araki, et.al., Exchangeable gene trap using the Cre/mutated lox system., Cellular and molecular biology (Noisy-le-Grand, France), 1999, 45
  http://rdf.ncbi.nlm.nih.gov/pubmed/10512203
• Jeffrey A. Ecsedy, et.al., Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity., Molecular and cellular biology, 2003, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/12529400
• Kyoichi. Isono, et.al., Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals., Molecular and cellular biology, 2006, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/16537918
• V. Rochat-Steiner, et.al., FIST/HIPK3: a Fas/FADD-interacting serine/threonine kinase that induces FADD phosphorylation and inhibits fas-mediated Jun NH(2)-terminal kinase activation., The Journal of experimental medicine, 2000, 192
  http://rdf.ncbi.nlm.nih.gov/pubmed/11034606

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• negative regulation of JUN kinase activity
  http://purl.obolibrary.org/obo/GO_0043508
• nucleotide binding
  http://purl.obolibrary.org/obo/GO_0000166
• transferase activity
  http://purl.obolibrary.org/obo/GO_0016740
• protein serine/threonine kinase activity
  http://purl.obolibrary.org/obo/GO_0004674
• phosphorylation
  http://purl.obolibrary.org/obo/GO_0016310
• kinase activity
  http://purl.obolibrary.org/obo/GO_0016301
• protein phosphorylation
  http://purl.obolibrary.org/obo/GO_0006468
• transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006351
• negative regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0000122
• transcription corepressor activity
  http://purl.obolibrary.org/obo/GO_0003714
• transferase activity, transferring phosphorus-containing groups
  http://purl.obolibrary.org/obo/GO_0016772
• protein kinase activity
  http://purl.obolibrary.org/obo/GO_0004672
• ATP binding
  http://purl.obolibrary.org/obo/GO_0005524
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• peptidyl-threonine phosphorylation
  http://purl.obolibrary.org/obo/GO_0018107
• regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006355
• apoptotic process
  http://purl.obolibrary.org/obo/GO_0006915
• PML body
  http://purl.obolibrary.org/obo/GO_0016605
• DNA binding
  http://purl.obolibrary.org/obo/GO_0003677
• mRNA transcription
  http://purl.obolibrary.org/obo/GO_0009299
• negative regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0043066
• positive regulation of DNA binding
  http://purl.obolibrary.org/obo/GO_0043388
• peptidyl-serine phosphorylation
  http://purl.obolibrary.org/obo/GO_0018105

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName