CD01108

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD01108

CD01108

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Dock1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• dedicator of cytokinesis 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• dedicator of cytokinesis 1
• dedicator of cyto-kinesis 1
• 180 kDa protein downstream of CRK
• dedicator of cytokinesis protein 1
• DOCK180

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• D630004B07Rik
• AI854900
• 9130006G06Rik
• Dock180

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/330662

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• dedicator of cytokinesis 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:2429765

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001033420

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000058325

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.436572

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=601403

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• S. Kobayashi, et.al., Membrane recruitment of DOCK180 by binding to PtdIns(3,4,5)P3., The Biochemical journal, 2001, 354
  http://rdf.ncbi.nlm.nih.gov/pubmed/11171081
• A. Kashiwa, et.al., Isolation and characterization of novel presenilin binding protein., Journal of neurochemistry, 2000, 75
  http://rdf.ncbi.nlm.nih.gov/pubmed/10854253
• K. Araki, et.al., Exchangeable gene trap using the Cre/mutated lox system., Cellular and molecular biology (Noisy-le-Grand, France), 1999, 45
  http://rdf.ncbi.nlm.nih.gov/pubmed/10512203
• Doug. Stryke, et.al., BayGenomics: a resource of insertional mutations in mouse embryonic stem cells., Nucleic acids research, 2003, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/12520002
• Yu. Lei, et.al., Role of DOCK2 and DOCK180 in fetal thymus colonization., European journal of immunology, 2009, 39
  http://rdf.ncbi.nlm.nih.gov/pubmed/19728314
• Richard J. Mural, et.al., A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome., Science (New York, N.Y.), 2002, 296
  http://rdf.ncbi.nlm.nih.gov/pubmed/12040188
• E. Kiyokawa, et.al., Evidence that DOCK180 up-regulates signals from the CrkII-p130(Cas) complex., The Journal of biological chemistry, 1998, 273
  http://rdf.ncbi.nlm.nih.gov/pubmed/9733740
• H. Hasegawa, et.al., DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane., Molecular and cellular biology, 1996, 16
  http://rdf.ncbi.nlm.nih.gov/pubmed/8657152
• Mélanie. Laurin, et.al., The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo., Proceedings of the National Academy of Sciences of the United States of America, 2008, 105
  http://rdf.ncbi.nlm.nih.gov/pubmed/18820033
• Xiaowen. He, et.al., Rac1 is essential for basement membrane-dependent epiblast survival., Molecular and cellular biology, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20457815
• Hironori. Katoh, et.al., RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo., Nature, 2003, 424
  http://rdf.ncbi.nlm.nih.gov/pubmed/12879077
• Xiaoling. Li, et.al., Netrin signal transduction and the guanine nucleotide exchange factor DOCK180 in attractive signaling., Nature neuroscience, 2008, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/18066058
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• phagocytosis
  http://purl.obolibrary.org/obo/GO_0006909
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• GTP binding
  http://purl.obolibrary.org/obo/GO_0005525
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• cell migration
  http://purl.obolibrary.org/obo/GO_0016477
• GTPase binding
  http://purl.obolibrary.org/obo/GO_0051020
• apoptotic process
  http://purl.obolibrary.org/obo/GO_0006915
• regulation of catalytic activity
  http://purl.obolibrary.org/obo/GO_0050790
• SH3 domain binding
  http://purl.obolibrary.org/obo/GO_0017124
• guanyl-nucleotide exchange factor activity
  http://purl.obolibrary.org/obo/GO_0005085

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map05100
• http://www.genome.jp/dbget-bin/www_bget?map04810
• http://www.genome.jp/dbget-bin/www_bget?map04510

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Bacterial invasion of epithelial cells
• Focal adhesion
• Regulation of actin cytoskeleton