CD01149

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD01149

CD01149

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Ephx1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• epoxide hydrolase 1, microsomal

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• epoxide hydratase
• epoxide hydrolase 1, microsomal
• epoxide hydrolase 1
• microsomal epoxide hydrolase

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• AI195553
• Eph-1
• Eph1
• mEH

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/13849

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• epoxide hydrolase 1, microsomal
  http://metadb.riken.jp/db/mgi_rdf/MGI:95405

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_010145

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000038776

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.9075

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=132810

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• E. Teissier, et.al., Drug metabolism in in vitro organotypic and cellular models of mammalian central nervous system: activities of membrane-bound epoxide hydrolase and NADPH-cytochrome P-450 (c) reductase., Neurotoxicology, 1998, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/9621341
• V L. Traina, et.al., Genetic mapping of endogenous mouse mammary tumor viruses: locus characterization, segregation, and chromosomal distribution., Journal of virology, 1981, 40
  http://rdf.ncbi.nlm.nih.gov/pubmed/6275115
• Aileen F. Keating, et.al., Effect of CYP2E1 gene deletion in mice on expression of microsomal epoxide hydrolase in response to VCD exposure., Toxicological sciences : an official journal of the Society of Toxicology, 2008, 105
  http://rdf.ncbi.nlm.nih.gov/pubmed/18622027
• Nathan R. McElroy, et.al., QSAR and classification of murine and human soluble epoxide hydrolase inhibition by urea-like compounds., Journal of medicinal chemistry, 2003, 46
  http://rdf.ncbi.nlm.nih.gov/pubmed/12620084
• Eun-Joo. Shin, et.al., Role of microsomal epoxide hydrolase in methamphetamine-induced drug dependence in mice., Journal of neuroscience research, 2009, 87
  http://rdf.ncbi.nlm.nih.gov/pubmed/19598248
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• K. Huppi, et.al., Sequence and organization of the mouse poly (ADP-ribose) polymerase gene., Nucleic acids research, 1989, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/2498841
• D F. Grant, et.al., Molecular cloning and expression of murine liver soluble epoxide hydrolase., The Journal of biological chemistry, 1993, 268
  http://rdf.ncbi.nlm.nih.gov/pubmed/8349642
• R C. Skoda, et.al., Human microsomal xenobiotic epoxide hydrolase. Complementary DNA sequence, complementary DNA-directed expression in COS-1 cells, and chromosomal localization., The Journal of biological chemistry, 1988, 263
  http://rdf.ncbi.nlm.nih.gov/pubmed/2891713
• A. Marowsky, et.al., Distribution of soluble and microsomal epoxide hydrolase in the mouse brain and its contribution to cerebral epoxyeicosatrienoic acid metabolism., Neuroscience, 2009, 163
  http://rdf.ncbi.nlm.nih.gov/pubmed/19540314
• F J. Gonzalez, et.al., Cloning of epoxide hydratase complementary DNA., The Journal of biological chemistry, 1981, 256
  http://rdf.ncbi.nlm.nih.gov/pubmed/6262298
• Ana W Y. Cheong, et.al., Oviductal microsomal epoxide hydrolase (EPHX1) reduces reactive oxygen species (ROS) level and enhances preimplantation mouse embryo development., Biology of reproduction, 2009, 81
  http://rdf.ncbi.nlm.nih.gov/pubmed/19321813
• D L. Simmons, et.al., Chromosomal assignments of genes coding for components of the mixed-function oxidase system in mice. Genetic localization of the cytochrome P-450PCN and P-450PB gene families and the nadph-cytochrome P-450 oxidoreductase and epoxide hydratase genes., The Journal of biological chemistry, 1985, 260
  http://rdf.ncbi.nlm.nih.gov/pubmed/3917435

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• endoplasmic reticulum
  http://purl.obolibrary.org/obo/GO_0005783
• catalytic activity
  http://purl.obolibrary.org/obo/GO_0003824
• hydrolase activity
  http://purl.obolibrary.org/obo/GO_0016787
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• metabolic process
  http://purl.obolibrary.org/obo/GO_0008152
• aromatic compound catabolic process
  http://purl.obolibrary.org/obo/GO_0019439
• cellular aromatic compound metabolic process
  http://purl.obolibrary.org/obo/GO_0006725
• enzyme binding
  http://purl.obolibrary.org/obo/GO_0019899
• epoxide hydrolase activity
  http://purl.obolibrary.org/obo/GO_0004301
• cis-stilbene-oxide hydrolase activity
  http://purl.obolibrary.org/obo/GO_0033961
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• microsome
  http://purl.obolibrary.org/obo/GO_0005792
• response to organic cyclic compound
  http://purl.obolibrary.org/obo/GO_0014070

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map00980
• http://www.genome.jp/dbget-bin/www_bget?map04976

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Bile secretion
• Metabolism of xenobiotics by cytochrome P450