CD01235

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD01235

CD01235

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Senp2

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• SUMO/sentrin specific peptidase 2

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• SUMO-1 protease-1
• axam2
• SUMO-1/Smt3-specific isopeptidase 2
• SUMO-1 protease 1
• SUMO/sentrin specific protease 2
• SUMO/sentrin specific peptidase 2
• sentrin-specific protease 2
• sentrin/SUMO-specific protease SENP2

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• AW554757
• axam2
• mKIAA1331
• SUMO-1
• 2310007L05Rik
• AI646780
• 4930538C18Rik
• SuPr-1
• Smt3ip2

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/75826

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• SUMO/sentrin specific peptidase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1923076

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_029457

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000022855

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.297431

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=608261

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Roland H. Friedel, et.al., EUCOMM--the European conditional mouse mutagenesis program., Briefings in functional genomics & proteomics, 2007, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/17967808
• Sung Soo. Chung, et.al., Control of adipogenesis by the SUMO-specific protease SENP2., Molecular and cellular biology, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20194620
• Pablo. Gómez-del Arco, et.al., Ikaros SUMOylation: switching out of repression., Molecular and cellular biology, 2005, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/15767674
• Sung Soo. Chung, et.al., SUMO modification selectively regulates transcriptional activity of peroxisome-proliferator-activated receptor γ in C2C12 myotubes., The Biochemical journal, 2011, 433
  http://rdf.ncbi.nlm.nih.gov/pubmed/20950277
• Gemma. Martinez, et.al., Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation., Investigative ophthalmology & visual science, 2009, 50
  http://rdf.ncbi.nlm.nih.gov/pubmed/19515997
• Shang-Yi. Chiu, et.al., SUMO-specific protease 2 is essential for modulating p53-Mdm2 in development of trophoblast stem cell niches and lineages., PLoS biology, 2008, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/19090619
• Susan. Magdaleno, et.al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system., PLoS biology, 2006, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/16602821
• T. Nishida, et.al., Characterization of a novel mammalian SUMO-1/Smt3-specific isopeptidase, a homologue of rat axam, which is an axin-binding protein promoting beta-catenin degradation., The Journal of biological chemistry, 2001, 276
  http://rdf.ncbi.nlm.nih.gov/pubmed/11489887
• Jennifer L. Best, et.al., SUMO-1 protease-1 regulates gene transcription through PML., Molecular cell, 2002, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/12419228
• Xunlei. Kang, et.al., SUMO-specific protease 2 is essential for suppression of polycomb group protein-mediated gene silencing during embryonic development., Molecular cell, 2010, 38
  http://rdf.ncbi.nlm.nih.gov/pubmed/20417598

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• proteolysis
  http://purl.obolibrary.org/obo/GO_0006508
• SUMO-specific protease activity
  http://purl.obolibrary.org/obo/GO_0016929
• transport
  http://purl.obolibrary.org/obo/GO_0006810
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• peptidase activity
  http://purl.obolibrary.org/obo/GO_0008233
• regulation of protein metabolic process
  http://purl.obolibrary.org/obo/GO_0051246
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• Wnt signaling pathway
  http://purl.obolibrary.org/obo/GO_0016055
• protein desumoylation
  http://purl.obolibrary.org/obo/GO_0016926
• cytoplasmic vesicle
  http://purl.obolibrary.org/obo/GO_0031410
• nuclear pore
  http://purl.obolibrary.org/obo/GO_0005643
• protein transport
  http://purl.obolibrary.org/obo/GO_0015031
• cysteine-type peptidase activity
  http://purl.obolibrary.org/obo/GO_0008234
• hydrolase activity
  http://purl.obolibrary.org/obo/GO_0016787
• transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006351
• negative regulation of protein binding
  http://purl.obolibrary.org/obo/GO_0032091
• mRNA transport
  http://purl.obolibrary.org/obo/GO_0051028
• protein domain specific binding
  http://purl.obolibrary.org/obo/GO_0019904
• PML body
  http://purl.obolibrary.org/obo/GO_0016605
• positive regulation of protein phosphorylation
  http://purl.obolibrary.org/obo/GO_0001934
• dorsal/ventral axis specification
  http://purl.obolibrary.org/obo/GO_0009950
• regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006355

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04310
• http://www.genome.jp/dbget-bin/www_bget?map03013

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Wnt signaling pathway
• RNA transport