CD01285

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD01285

CD01285

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Carm1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• coactivator-associated arginine methyltransferase 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• histone-arginine methyltransferase CARM1
• protein arginine methyltransferase
• protein arginine N-methyltransferase 4
• coactivator-associated arginine methyltransferase 1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Prmt4

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/59035

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• coactivator-associated arginine methyltransferase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1913208

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_021531
• https://www.ncbi.nlm.nih.gov/nuccore/NM_153141

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000032185

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.178115

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=603934

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Elisabeth. Kowenz-Leutz, et.al., Crosstalk between C/EBPbeta phosphorylation, arginine methylation, and SWI/SNF/Mediator implies an indexing transcription factor code., The EMBO journal, 2010, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/20111005
• H. Ma, et.al., Hormone-dependent, CARM1-directed, arginine-specific methylation of histone H3 on a steroid-regulated promoter., Current biology : CB, 2001, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/11747826
• B T. Schurter, et.al., Methylation of histone H3 by coactivator-associated arginine methyltransferase 1., Biochemistry, 2001, 40
  http://rdf.ncbi.nlm.nih.gov/pubmed/11341840
• W. Xu, et.al., A transcriptional switch mediated by cofactor methylation., Science (New York, N.Y.), 2001, 294
  http://rdf.ncbi.nlm.nih.gov/pubmed/11701890
• Young-Ho. Lee, et.al., Regulated recruitment of tumor suppressor BRCA1 to the p21 gene by coactivator methylation., Genes & development, 2011, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/21245169
• Karen B. O'Brien, et.al., CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial cells., Development (Cambridge, England), 2010, 137
  http://rdf.ncbi.nlm.nih.gov/pubmed/20530543
• Shen Liang. Chen, et.al., The coactivator-associated arginine methyltransferase is necessary for muscle differentiation: CARM1 coactivates myocyte enhancer factor-2., The Journal of biological chemistry, 2002, 277
  http://rdf.ncbi.nlm.nih.gov/pubmed/11713257
• Shigetoshi. Yokoyama, et.al., A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58., Developmental cell, 2009, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/20059953
• Stephen S. Koh, et.al., Synergistic coactivator function by coactivator-associated arginine methyltransferase (CARM) 1 and beta-catenin with two different classes of DNA-binding transcriptional activators., The Journal of biological chemistry, 2002, 277
  http://rdf.ncbi.nlm.nih.gov/pubmed/11983685
• Jeesun. Kim, et.al., Loss of CARM1 results in hypomethylation of thymocyte cyclic AMP-regulated phosphoprotein and deregulated early T cell development., The Journal of biological chemistry, 2004, 279
  http://rdf.ncbi.nlm.nih.gov/pubmed/15096520
• Daehoon. Kim, et.al., Enzymatic activity is required for the in vivo functions of CARM1., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/19897492
• D. Chen, et.al., Regulation of transcription by a protein methyltransferase., Science (New York, N.Y.), 1999, 284
  http://rdf.ncbi.nlm.nih.gov/pubmed/10381882

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• protein homodimerization activity
  http://purl.obolibrary.org/obo/GO_0042803
• protein-arginine N-methyltransferase activity
  http://purl.obolibrary.org/obo/GO_0016274
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• intracellular steroid hormone receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0030518
• transferase activity
  http://purl.obolibrary.org/obo/GO_0016740
• histone methyltransferase activity (H3-R17 specific)
  http://purl.obolibrary.org/obo/GO_0035642
• histone-arginine N-methyltransferase activity
  http://purl.obolibrary.org/obo/GO_0008469
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• methylation
  http://purl.obolibrary.org/obo/GO_0032259
• protein methyltransferase activity
  http://purl.obolibrary.org/obo/GO_0008276
• negative regulation of protein binding
  http://purl.obolibrary.org/obo/GO_0032091
• positive regulation of cell proliferation
  http://purl.obolibrary.org/obo/GO_0008284
• regulation of growth plate cartilage chondrocyte proliferation
  http://purl.obolibrary.org/obo/GO_0003420
• protein-arginine omega-N asymmetric methyltransferase activity
  http://purl.obolibrary.org/obo/GO_0035242
• peptidyl-arginine N-methylation
  http://purl.obolibrary.org/obo/GO_0035246
• pathogenesis
  http://purl.obolibrary.org/obo/GO_0009405
• transcription coactivator activity
  http://purl.obolibrary.org/obo/GO_0003713
• chromatin organization
  http://purl.obolibrary.org/obo/GO_0006325
• transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006351
• regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006355
• histone H3-R17 methylation
  http://purl.obolibrary.org/obo/GO_0034971
• endochondral bone morphogenesis
  http://purl.obolibrary.org/obo/GO_0060350
• covalent chromatin modification
  http://purl.obolibrary.org/obo/GO_0016569
• histone methyltransferase activity
  http://purl.obolibrary.org/obo/GO_0042054
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• methyltransferase activity
  http://purl.obolibrary.org/obo/GO_0008168
• ligand-dependent nuclear receptor transcription coactivator activity
  http://purl.obolibrary.org/obo/GO_0030374
• positive regulation of fat cell differentiation
  http://purl.obolibrary.org/obo/GO_0045600
• response to cAMP
  http://purl.obolibrary.org/obo/GO_0051591
• histone H3-R2 methylation
  http://purl.obolibrary.org/obo/GO_0034970
• transcription regulatory region DNA binding
  http://purl.obolibrary.org/obo/GO_0044212
• histone arginine methylation
  http://purl.obolibrary.org/obo/GO_0034969
• histone methylation
  http://purl.obolibrary.org/obo/GO_0016571
• regulation of intracellular estrogen receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0033146

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName