CD01343

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD01343

CD01343

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Rps6ka1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• ribosomal protein S6 kinase polypeptide 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• p90RSK1
• ribosomal S6 kinase 1
• MAPKAP kinase 1a
• Ribosomal protein S6 kinase, 90kD, 1
• ribosomal protein S6 kinase alpha-1
• MAPKAPK-1a
• 90 kDa ribosomal protein S6 kinase 1
• RSK-1
• ribosomal protein S6 kinase, 90kD, polypeptide 1
• S6K-alpha-1
• ribosomal protein S6 kinase polypeptide 1
• p90-RSK 1
• p90S6K
• MAP kinase-activated protein kinase 1a
• MAPK-activated protein kinase 1a

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• rsk
• Rsk1
• p90rsk

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/20111

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• ribosomal protein S6 kinase polypeptide 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:104558

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_009097

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000003644

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.301827

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=601684

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• D A. Alcorta, et.al., Sequence and expression of chicken and mouse rsk: homologs of Xenopus laevis ribosomal S6 kinase., Molecular and cellular biology, 1989, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/2779569
• K. Engel, et.al., The MAP kinase-activated protein kinase 2 contains a proline-rich SH3-binding domain., FEBS letters, 1993, 336
  http://rdf.ncbi.nlm.nih.gov/pubmed/8262198
• Deepti. Chaturvedi, et.al., The PKARIalpha subunit of protein kinase A modulates the activation of p90RSK1 and its function., The Journal of biological chemistry, 2009, 284
  http://rdf.ncbi.nlm.nih.gov/pubmed/19570980
• D J. Spring, et.al., Deletion of 11 amino acids in p90(rsk-mo-1) abolishes kinase activity., Molecular and cellular biology, 1999, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/9858555
• Joseph B. McPhee, et.al., Delineation of regions of the Yersinia YopM protein required for interaction with the RSK1 and PRK2 host kinases and their requirement for interleukin-10 production and virulence., Infection and immunity, 2010, 78
  http://rdf.ncbi.nlm.nih.gov/pubmed/20515922
• L. Cheatham, et.al., Structural and functional analysis of pp70S6k., Proceedings of the National Academy of Sciences of the United States of America, 1995, 92
  http://rdf.ncbi.nlm.nih.gov/pubmed/8524831
• Berta. Casar, et.al., Ras subcellular localization defines extracellular signal-regulated kinase 1 and 2 substrate specificity through distinct utilization of scaffold proteins., Molecular and cellular biology, 2009, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/19114553
• Namratta. Manhas, et.al., p90 activation contributes to cerebral ischemic damage via phosphorylation of Na+/H+ exchanger isoform 1., Journal of neurochemistry, 2010, 114
  http://rdf.ncbi.nlm.nih.gov/pubmed/20557427
• H. Kawasome, et.al., Targeted disruption of p70(s6k) defines its role in protein synthesis and rapamycin sensitivity., Proceedings of the National Academy of Sciences of the United States of America, 1998, 95
  http://rdf.ncbi.nlm.nih.gov/pubmed/9560223

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• protein kinase activity
  http://purl.obolibrary.org/obo/GO_0004672
• phosphorylation
  http://purl.obolibrary.org/obo/GO_0016310
• intracellular signal transduction
  http://purl.obolibrary.org/obo/GO_0035556
• positive regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0045893
• protein serine/threonine kinase activity
  http://purl.obolibrary.org/obo/GO_0004674
• magnesium ion binding
  http://purl.obolibrary.org/obo/GO_0000287
• spindle
  http://purl.obolibrary.org/obo/GO_0005819
• transferase activity
  http://purl.obolibrary.org/obo/GO_0016740
• transcription factor binding
  http://purl.obolibrary.org/obo/GO_0008134
• protein phosphorylation
  http://purl.obolibrary.org/obo/GO_0006468
• kinase activity
  http://purl.obolibrary.org/obo/GO_0016301
• positive regulation of hepatic stellate cell activation
  http://purl.obolibrary.org/obo/GO_2000491
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
  http://purl.obolibrary.org/obo/GO_0043154
• ribosome
  http://purl.obolibrary.org/obo/GO_0005840
• ATP binding
  http://purl.obolibrary.org/obo/GO_0005524
• nucleotide binding
  http://purl.obolibrary.org/obo/GO_0000166
• cysteine-type endopeptidase inhibitor activity involved in apoptotic process
  http://purl.obolibrary.org/obo/GO_0043027
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• transferase activity, transferring phosphorus-containing groups
  http://purl.obolibrary.org/obo/GO_0016772
• negative regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0043066

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04150
• http://www.genome.jp/dbget-bin/www_bget?map04010
• http://www.genome.jp/dbget-bin/www_bget?map04722
• http://www.genome.jp/dbget-bin/www_bget?map04914
• http://www.genome.jp/dbget-bin/www_bget?map04720
• http://www.genome.jp/dbget-bin/www_bget?map04114

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Progesterone-mediated oocyte maturation
• Long-term potentiation
• Neurotrophin signaling pathway
• Oocyte meiosis
• MAPK signaling pathway
• mTOR signaling pathway