CD01457

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD01457

CD01457

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Sorbs1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• sorbin and SH3 domain containing 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• sorbin and SH3 domain-containing protein 1
• ponsin
• sorbin and SH3 domain containing 1
• SH3 domain protein 5

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• 2310065E01Rik
• 9530001P15Rik
• Ponsin
• SH3P12
• CAP
• Sh3d5
• mKIAA1296
• SORB1
• c-Cbl-associated protein

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/20411

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• sorbin and SH3 domain containing 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:700014

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001034963
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001034962
• https://www.ncbi.nlm.nih.gov/nuccore/NM_009166
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001034964
• https://www.ncbi.nlm.nih.gov/nuccore/NM_178362

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000025006

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.417719
• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.210815
• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.440351

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=605264

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• N G. Hoffman, et.al., Binding properties of SH3 peptide ligands identified from phage-displayed random peptide libraries., Molecular diversity, 1996, 2
  http://rdf.ncbi.nlm.nih.gov/pubmed/9238627
• A B. Sparks, et.al., Cloning of ligand targets: systematic isolation of SH3 domain-containing proteins., Nature biotechnology, 1996, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/9630982
• Daniela. Tosoni, et.al., CAP (Cbl associated protein) regulates receptor-mediated endocytosis., FEBS letters, 2009, 583
  http://rdf.ncbi.nlm.nih.gov/pubmed/19116150
• Katja. Gehmlich, et.al., Ponsin interacts with Nck adapter proteins: implications for a role in cytoskeletal remodelling during differentiation of skeletal muscle cells., European journal of cell biology, 2010, 89
  http://rdf.ncbi.nlm.nih.gov/pubmed/20129698
• V. Ribon, et.al., A novel, multifuntional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes., Molecular and cellular biology, 1998, 18
  http://rdf.ncbi.nlm.nih.gov/pubmed/9447983
• K. Mandai, et.al., Ponsin/SH3P12: an l-afadin- and vinculin-binding protein localized at cell-cell and cell-matrix adherens junctions., The Journal of cell biology, 1999, 144
  http://rdf.ncbi.nlm.nih.gov/pubmed/10085297
• Auinash. Kalsotra, et.al., A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart., Proceedings of the National Academy of Sciences of the United States of America, 2008, 105
  http://rdf.ncbi.nlm.nih.gov/pubmed/19075228
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Stephen N. Sansom, et.al., The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis., PLoS genetics, 2009, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/19521500
• V. Ribon, et.al., A role for CAP, a novel, multifunctional Src homology 3 domain-containing protein in formation of actin stress fibers and focal adhesions., The Journal of biological chemistry, 1998, 273
  http://rdf.ncbi.nlm.nih.gov/pubmed/9461600

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• transport
  http://purl.obolibrary.org/obo/GO_0006810
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• positive regulation of glucose import
  http://purl.obolibrary.org/obo/GO_0046326
• protein kinase binding
  http://purl.obolibrary.org/obo/GO_0019901
• cell junction
  http://purl.obolibrary.org/obo/GO_0030054
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• http://purl.obolibrary.org/obo/GO_1904659
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• cell-cell adherens junction
  http://purl.obolibrary.org/obo/GO_0005913
• centrosome
  http://purl.obolibrary.org/obo/GO_0005813
• stress fiber
  http://purl.obolibrary.org/obo/GO_0001725
• positive regulation of glycogen biosynthetic process
  http://purl.obolibrary.org/obo/GO_0045725
• membrane raft
  http://purl.obolibrary.org/obo/GO_0045121
• flotillin complex
  http://purl.obolibrary.org/obo/GO_0016600
• positive regulation of signal transduction
  http://purl.obolibrary.org/obo/GO_0009967
• cellular response to insulin stimulus
  http://purl.obolibrary.org/obo/GO_0032869
• SH3/SH2 adaptor activity
  http://purl.obolibrary.org/obo/GO_0005070
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• focal adhesion
  http://purl.obolibrary.org/obo/GO_0005925
• insulin receptor binding
  http://purl.obolibrary.org/obo/GO_0005158
• stress fiber assembly
  http://purl.obolibrary.org/obo/GO_0043149
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• cytoskeleton
  http://purl.obolibrary.org/obo/GO_0005856
• cell-substrate adherens junction
  http://purl.obolibrary.org/obo/GO_0005924
• insulin receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0008286
• positive regulation of lipid biosynthetic process
  http://purl.obolibrary.org/obo/GO_0046889
• focal adhesion assembly
  http://purl.obolibrary.org/obo/GO_0048041

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map03320
• http://www.genome.jp/dbget-bin/www_bget?map04910
• http://www.genome.jp/dbget-bin/www_bget?map04520

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Adherens junction
• Insulin signaling pathway
• PPAR signaling pathway