CD01470

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD01470

CD01470

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Cd2ap

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• CD2-associated protein

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• mesenchyme-to-epithelium transition protein with SH3 domains 1
• CD2-associated protein
• SH3 domain-containing adaptor protein METS-1
• mesenchyme to epithelium transition protein, SH3 domains
• SH3 domain-containing adapter protein

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• C78928
• AL024079
• Mets1
• METS-1

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/12488

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• CD2-associated protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:1330281

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_009847

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000061665

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.218637

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=604241

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• S. Lehtonen, et.al., In vivo interaction of the adapter protein CD2-associated protein with the type 2 polycystic kidney disease protein, polycystin-2., The Journal of biological chemistry, 2000, 275
  http://rdf.ncbi.nlm.nih.gov/pubmed/10913159
• N Y. Shih, et.al., CD2AP localizes to the slit diaphragm and binds to nephrin via a novel C-terminal domain., The American journal of pathology, 2001, 159
  http://rdf.ncbi.nlm.nih.gov/pubmed/11733379
• Irini. Tossidou, et.al., CIN85/RukL is a novel binding partner of nephrin and podocin and mediates slit diaphragm turnover in podocytes., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20457601
• S. Jansson, et.al., Mouse metanephric kidney as a model system for identifying developmentally regulated genes., Journal of cellular physiology, 1997, 173
  http://rdf.ncbi.nlm.nih.gov/pubmed/9365514
• Sandhya. Xavier, et.al., TbetaRI independently activates Smad- and CD2AP-dependent pathways in podocytes., Journal of the American Society of Nephrology : JASN, 2009, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/19679673
• Alexander N. Combes, et.al., Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development., Developmental dynamics : an official publication of the American Association of Anatomists, 2009, 238
  http://rdf.ncbi.nlm.nih.gov/pubmed/19334288
• M L. Dustin, et.al., A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts., Cell, 1998, 94
  http://rdf.ncbi.nlm.nih.gov/pubmed/9741631
• Chun. Zhang, et.al., Downregulation of CD2-associated protein impaired the physiological functions of podocytes., Cell biology international, 2009, 33
  http://rdf.ncbi.nlm.nih.gov/pubmed/19306938
• N Y. Shih, et.al., Congenital nephrotic syndrome in mice lacking CD2-associated protein., Science (New York, N.Y.), 1999, 286
  http://rdf.ncbi.nlm.nih.gov/pubmed/10514378
• T. Welsch, et.al., CD2AP and p130Cas localize to different F-actin structures in podocytes., American journal of physiology. Renal physiology, 2001, 281
  http://rdf.ncbi.nlm.nih.gov/pubmed/11553524
• Sanna. Lehtonen, et.al., CD2-associated protein directly interacts with the actin cytoskeleton., American journal of physiology. Renal physiology, 2002, 283
  http://rdf.ncbi.nlm.nih.gov/pubmed/12217865
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• cell cycle
  http://purl.obolibrary.org/obo/GO_0007049
• regulation of receptor-mediated endocytosis
  http://purl.obolibrary.org/obo/GO_0048259
• macromolecular complex binding
  http://purl.obolibrary.org/obo/GO_0044877
• cytoskeleton
  http://purl.obolibrary.org/obo/GO_0005856
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• cell cortex
  http://purl.obolibrary.org/obo/GO_0005938
• ruffle
  http://purl.obolibrary.org/obo/GO_0001726
• cell-cell adhesion
  http://purl.obolibrary.org/obo/GO_0098609
• cell division
  http://purl.obolibrary.org/obo/GO_0051301
• perinuclear region of cytoplasm
  http://purl.obolibrary.org/obo/GO_0048471
• macromolecular complex
  http://purl.obolibrary.org/obo/GO_0032991
• SH3 domain binding
  http://purl.obolibrary.org/obo/GO_0017124
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• filamentous actin
  http://purl.obolibrary.org/obo/GO_0031941
• cell leading edge
  http://purl.obolibrary.org/obo/GO_0031252
• endocytic vesicle
  http://purl.obolibrary.org/obo/GO_0030139
• vesicle organization
  http://purl.obolibrary.org/obo/GO_0016050
• proteasome-mediated ubiquitin-dependent protein catabolic process
  http://purl.obolibrary.org/obo/GO_0043161
• cell migration
  http://purl.obolibrary.org/obo/GO_0016477
• cadherin binding
  http://purl.obolibrary.org/obo/GO_0045296
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• cell projection
  http://purl.obolibrary.org/obo/GO_0042995
• protein C-terminus binding
  http://purl.obolibrary.org/obo/GO_0008022
• beta-catenin binding
  http://purl.obolibrary.org/obo/GO_0008013
• vascular endothelial growth factor receptor binding
  http://purl.obolibrary.org/obo/GO_0005172
• mitotic cell cycle
  http://purl.obolibrary.org/obo/GO_0000278
• nucleolus
  http://purl.obolibrary.org/obo/GO_0005730

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map05100

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Bacterial invasion of epithelial cells