CD01645

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD01645

CD01645

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Ggcx

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• gamma-glutamyl carboxylase

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• peptidyl-glutamate 4-carboxylase
• vitamin K-dependent gamma-carboxylase
• gamma-carboxylase
• gamma-glutamyl carboxylase
• vitamin K gamma glutamyl carboxylase

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• vitamin K-dependent carboxylase

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/56316

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• gamma-glutamyl carboxylase
  http://metadb.riken.jp/db/mgi_rdf/MGI:1927655

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_019802

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000053460

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.19937

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=137167

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Shannon L. Higgins-Gruber, et.al., Effect of vitamin K-dependent protein precursor propeptide, vitamin K hydroquinone, and glutamate substrate binding on the structure and function of {gamma}-glutamyl carboxylase., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20716530
• Qiaoli. Li, et.al., The mineralization phenotype in Abcc6 ( -/- ) mice is affected by Ggcx gene deficiency and genetic background--a model for pseudoxanthoma elasticum., Journal of molecular medicine (Berlin, Germany), 2010, 88
  http://rdf.ncbi.nlm.nih.gov/pubmed/19784827
• G S. Begley, et.al., A conserved motif within the vitamin K-dependent carboxylase gene is widely distributed across animal phyla., The Journal of biological chemistry, 2000, 275
  http://rdf.ncbi.nlm.nih.gov/pubmed/10893417
• E E. Romero, et.al., Cloning of rat vitamin K-dependent gamma-glutamyl carboxylase and developmentally regulated gene expression in postimplantation embryos., Experimental cell research, 1998, 243
  http://rdf.ncbi.nlm.nih.gov/pubmed/9743593
• Reidar. Wallin, et.al., Vitamin K 2,3-epoxide reductase and the vitamin K-dependent gamma-carboxylation system., Thrombosis research, 2002, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/12617985
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• B N. Pudota, et.al., Identification of sequences within the gamma-carboxylase that represent a novel contact site with vitamin K-dependent proteins and that are required for activity., The Journal of biological chemistry, 2001, 276
  http://rdf.ncbi.nlm.nih.gov/pubmed/11591726
• Eva. Czerwiec, et.al., Expression and characterization of recombinant vitamin K-dependent gamma-glutamyl carboxylase from an invertebrate, Conus textile., European journal of biochemistry, 2002, 269
  http://rdf.ncbi.nlm.nih.gov/pubmed/12473112
• Aihua. Zhu, et.al., Fatal hemorrhage in mice lacking gamma-glutamyl carboxylase., Blood, 2007, 109
  http://rdf.ncbi.nlm.nih.gov/pubmed/17327402

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• metabolic process
  http://purl.obolibrary.org/obo/GO_0008152
• lyase activity
  http://purl.obolibrary.org/obo/GO_0016829
• endoplasmic reticulum
  http://purl.obolibrary.org/obo/GO_0005783
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• peptidyl-glutamic acid carboxylation
  http://purl.obolibrary.org/obo/GO_0017187
• gamma-glutamyl carboxylase activity
  http://purl.obolibrary.org/obo/GO_0008488

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName