CD01802

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD01802

CD01802

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Hcn1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• hyperpolarization-activated, cyclic nucleotide-gated K+ 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• HAC-2
• brain cyclic nucleotide-gated channel 1
• BCNG-1
• hyperpolarization-activated cation channel 2
• hyperpolarization-activated, cyclic nucleotide-gated K+ 1
• potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• C630013B14Rik
• Bcng1
• HAC2

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/15165

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• hyperpolarization-activated, cyclic nucleotide-gated K+ 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1096392

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_010408

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000021730

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.343429

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=602780

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• B. Santoro, et.al., Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to eag and cyclic nucleotide-gated channels., Proceedings of the National Academy of Sciences of the United States of America, 1997, 94
  http://rdf.ncbi.nlm.nih.gov/pubmed/9405696
• Xiangdong. Chen, et.al., Homeostatic regulation of synaptic excitability: tonic GABA(A) receptor currents replace I(h) in cortical pyramidal neurons of HCN1 knock-out mice., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20164346
• A. Moroni, et.al., Hyperpolarization-activated cyclic nucleotide-gated channel 1 is a molecular determinant of the cardiac pacemaker current I(f)., The Journal of biological chemistry, 2001, 276
  http://rdf.ncbi.nlm.nih.gov/pubmed/11328811
• Bina. Santoro, et.al., Increased seizure severity and seizure-related death in mice lacking HCN1 channels., Epilepsia, 2010, 51
  http://rdf.ncbi.nlm.nih.gov/pubmed/20384728
• Nadine L. Wicks, et.al., Cytoplasmic cAMP-sensing domain of hyperpolarization-activated cation (HCN) channels uses two structurally distinct mechanisms to regulate voltage gating., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21187420
• A. Ludwig, et.al., A family of hyperpolarization-activated mammalian cation channels., Nature, 1998, 393
  http://rdf.ncbi.nlm.nih.gov/pubmed/9634236
• B. Santoro, et.al., Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain., Cell, 1998, 93
  http://rdf.ncbi.nlm.nih.gov/pubmed/9630217
• Arie S. Mobley, et.al., Hyperpolarization-activated cyclic nucleotide-gated channels in olfactory sensory neurons regulate axon extension and glomerular formation., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/21147989
• http://rdf.ncbi.nlm.nih.gov/pubmed/21052544
• H. Yu, et.al., MinK-related peptide 1: A beta subunit for the HCN ion channel subunit family enhances expression and speeds activation., Circulation research, 2001, 88
  http://rdf.ncbi.nlm.nih.gov/pubmed/11420311

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• regulation of ion transmembrane transport
  http://purl.obolibrary.org/obo/GO_0034765
• transport
  http://purl.obolibrary.org/obo/GO_0006810
• potassium ion transmembrane transport
  http://purl.obolibrary.org/obo/GO_0071805
• transmembrane transport
  http://purl.obolibrary.org/obo/GO_0055085
• dendrite
  http://purl.obolibrary.org/obo/GO_0030425
• sodium channel activity
  http://purl.obolibrary.org/obo/GO_0005272
• sodium ion transmembrane transport
  http://purl.obolibrary.org/obo/GO_0035725
• cAMP binding
  http://purl.obolibrary.org/obo/GO_0030552
• ion channel activity
  http://purl.obolibrary.org/obo/GO_0005216
• retinal cone cell development
  http://purl.obolibrary.org/obo/GO_0046549
• potassium channel activity
  http://purl.obolibrary.org/obo/GO_0005267
• voltage-gated potassium channel activity
  http://purl.obolibrary.org/obo/GO_0005249
• ion transport
  http://purl.obolibrary.org/obo/GO_0006811
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• potassium ion transport
  http://purl.obolibrary.org/obo/GO_0006813
• sodium ion transport
  http://purl.obolibrary.org/obo/GO_0006814
• nucleotide binding
  http://purl.obolibrary.org/obo/GO_0000166
• voltage-gated ion channel activity
  http://purl.obolibrary.org/obo/GO_0005244
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• axon
  http://purl.obolibrary.org/obo/GO_0030424
• apical protein localization
  http://purl.obolibrary.org/obo/GO_0045176

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName